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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A02413-36 | Other Identifier | ID RCB |
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Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.
EPPICA is an observational and prospective cohort study. The study goal is to evaluate LUS aspect evolution according to diuretics dosage in patients hospitalized for acute heart failure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with acute heart failure | Patients hospitalized for acute heart failure in medical department. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lung ultrasound | Other | We will perform daily a lung ultrasound to evaluate pulmonary congestion by counting B-lines. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Lung ultrasound aspect according to diuretics dosage evolution. | B-lines number on LUS | LUS will be performed daily during the whole hospitalisation length (on average 7 days). |
| Measure | Description | Time Frame |
|---|---|---|
| Lung ultrasound aspect according to clinical signs of acute heart failure (crackling auscultation or lower limbs edema) | B-lines number on LUS | LUS and clinical examination will be performed daily during the whole hospitalisation length (on average 7 days). |
| Lung ultrasound aspect according to acute kidney injury (based on plasmatic creatinine levels). |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged over 18, hospitalized from the emergency department in the medical department for acute heart failure.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Perrine Dumanoir, Doctor | Contact | +33476767098 | pdumanoir@chu-grenoble.fr | |
| Mélanie Arnaud | Contact | +3376767098 | marnaud3@chu-grenoble.fr |
| Name | Affiliation | Role |
|---|---|---|
| Perrine Dumanoir, Doctor | University Hospital, Grenoble | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28960894 | Background | Ohman J, Harjola VP, Karjalainen P, Lassus J. Focused echocardiography and lung ultrasound protocol for guiding treatment in acute heart failure. ESC Heart Fail. 2018 Feb;5(1):120-128. doi: 10.1002/ehf2.12208. Epub 2017 Sep 28. | |
| 26417699 | Background | Coiro S, Rossignol P, Ambrosio G, Carluccio E, Alunni G, Murrone A, Tritto I, Zannad F, Girerd N. Prognostic value of residual pulmonary congestion at discharge assessed by lung ultrasound imaging in heart failure. Eur J Heart Fail. 2015 Nov;17(11):1172-81. doi: 10.1002/ejhf.344. Epub 2015 Sep 29. |
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B-lines number on LUS |
| LUS will be performed daily during the whole hospitalisation length (on average 7 days). Plasmatic creatinine measure will be performed at least weekly. |
| Lung ultrasound aspect according to early prognosis (re-hospitalisation or mortality within 30 days after discharge) | B-lines number on LUS | LUS will be performed daily during the whole hospitalisation length (on average 7 days). Patient will be called 30 days after discharge. |
| Feasibility of daily LUS in medical department. | Number of LUS performed compared to number of hospitalisation days. | LUS will be performed daily during the whole hospitalisation length (on average 7 days). |
| Interest of LUS compared to clinical examination at discharge. | B-lines at discharge compared to clinical signs of acute heart failure. | LUS and clinical examination will be performed daily during the whole hospitalisation length (on average 7 days). |
| 26337295 | Background | Gargani L, Pang PS, Frassi F, Miglioranza MH, Dini FL, Landi P, Picano E. Persistent pulmonary congestion before discharge predicts rehospitalization in heart failure: a lung ultrasound study. Cardiovasc Ultrasound. 2015 Sep 4;13:40. doi: 10.1186/s12947-015-0033-4. |
| 28557302 | Background | Platz E, Merz AA, Jhund PS, Vazir A, Campbell R, McMurray JJ. Dynamic changes and prognostic value of pulmonary congestion by lung ultrasound in acute and chronic heart failure: a systematic review. Eur J Heart Fail. 2017 Sep;19(9):1154-1163. doi: 10.1002/ejhf.839. Epub 2017 May 30. |
| 18534289 | Background | Volpicelli G, Caramello V, Cardinale L, Mussa A, Bar F, Frascisco MF. Bedside ultrasound of the lung for the monitoring of acute decompensated heart failure. Am J Emerg Med. 2008 Jun;26(5):585-91. doi: 10.1016/j.ajem.2007.09.014. |
| 31023358 | Background | Rusu DM, Siriopol I, Grigoras I, Blaj M, Ciumanghel AI, Siriopol D, Nistor I, Onofriescu M, Sandu G, Cobzaru B, Scripcariu DV, Diaconu O, Covic AC. Lung Ultrasound Guided Fluid Management Protocol for the Critically Ill Patient: study protocol for a multi-centre randomized controlled trial. Trials. 2019 Apr 25;20(1):236. doi: 10.1186/s13063-019-3345-0. |