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| Name | Class |
|---|---|
| University of Cambridge | OTHER |
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Musculoskeletal diseases, such as osteoarthritis, represent a large proportion of the global burden of disease with hip and knee osteoarthritis alone being the 11th greatest cause of disease burden.
The purpose of this study is to determine the level of musculoskeletal symptoms in members of the Cambridge National Institute for Health Research (NIHR) BioResource and see if this is associated with their possession of genetic markers that have been identified as being associated with osteoarthritis.
This will allow us to determine the real level of musculoskeletal symptoms in this large cohort of volunteers and provide basic information that could be used to facilitate further musculoskeletal research in the NIHR BioResource population.
All active members of the Cambridge NIHR BioResource will be approached.
They will be sent an email outlining the purpose of the study and asking that if they would like to take part to please complete the online questionnaire which will be linked to in the email.
For those individuals who agree to participate and complete the questionnaire, the Cambridge NIHR BioResource will provide the genetic marker information it already holds for specific markers that are known to be associated with osteoarthritis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Member of BioResource | Any BioResource member who consents to take part in the study and completes the study questionnaire. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Questionnaire including MSK-HQ (Musculoskeletal Health Questionnaire) | Other | A questionnaire regarding musculoskeletal past medical history and current symptoms. |
|
| Measure | Description | Time Frame |
|---|---|---|
| MSK Symptom Levels | Musculoskeletal Symptoms in respondents | 3 months |
| Osteoarthritis genetic marker | Possession (or not) of specific genetic markers for osteoarthritis (obtained from information already held by the NIHR BioResource) | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| MSK Cohort | Identification of those with particular musculoskeletal injuries and conditions for future studies | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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All members of the Cambridge NIHR BioResource
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Benjamin Davies | Contact | +44 1223 217551 | bmd35@cam.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Andrew McCaskie | University of Cambridge | Principal Investigator |
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Sharing of participant level data does not fall within the consent or ethical approval of the study.
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| ID | Term |
|---|---|
| D009140 | Musculoskeletal Diseases |
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