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The anastomotic leak (AL) is a very serious complication in colorectal surgery not only because of its severity but its frequency. Other facet for study, besides the risk factor and prevention, is the AL early diagnostic, due to minimize the clinical consequences and severity; and avoid the failure-to-recue. Several studies analyze the Creactive protein (CRP) and Procalcitonine (PCT) usefulness in AL predictor before the clinical signs appear.
At a prospective observational study carry on our center, it concluded that CRP at 3rd day after surgery over 15mg/dl was a very important AL predictor, even before the clinical changes appear. The aim of this study is minimize the severity complications and the mortality due to AL appears. The aim of this study is minimize the severity complications and the mortality due to AL by means of introduces an upgrade program in which a CT scan will be conduct in all the patients with high CRP levels at 3rd, 4th or 5th postoperative day, with the goal to know the AL early and make all the therapeutic step to minimize the consequences.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Early diagnosis | Other | Early diagnosis. Upgrade program implementation. |
| Measure | Description | Time Frame |
|---|---|---|
| Severity of morbidity | Number of reoperations, readmissions for infections associated or other medical complications, terminal stomata | 1 year |
| Severity of mortality | Number of related exits | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| - Compare hospital stay and ICU stay of patients undergoing elective colorectal surgery before and after the improvement program. | 1 year | |
| - Evaluate the difference in the incidence of anastomosis leak after the implementation of the improvement program |
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Inclusion Criteria:
Exclusion Criteria:
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All patients who underwent elective colorectal surgery consecutively will be included, in which an anastomosis have been performed (neoplastic and non-neoplastic pathology
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Graciela Valero-Navarro, MD | Contact | 968360900 | valerograciela@um.es |
| Name | Affiliation | Role |
|---|---|---|
| Graciela Valero-Navarro, MD | - Hospital Morales Meseguer | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| - Hospital Morales Meseguer | Recruiting | Murcia | 30003 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34018141 | Derived | Baeza-Murcia M, Valero-Navarro G, Pellicer-Franco E, Soria-Aledo V, Mengual-Ballester M, Garcia-Marin JA, Betoret-Benavente L, Aguayo-Albasini JL. Early diagnosis of anastomotic leakage in colorectal surgery: prospective observational study of the utility of inflammatory markers and determination of pathological levels. Updates Surg. 2021 Dec;73(6):2103-2111. doi: 10.1007/s13304-021-01082-8. Epub 2021 May 20. |
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| 1 year |