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Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there is no cure for COVID-19, except for supportive treatments. Quarantine for a defined period is the best option to reduce the spread of COVID-19. Physical activity has been shown to reduce the risk of serious community-acquired infections. However, it remains unanswered is whether physical activity has protective effects against SARS-CoV-2 infection and COVID-19 related mortality. This study aimed to examine the association of PA with the morbidity and mortality of COVID-19 infection in the entire South Korean population.
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| Measure | Description | Time Frame |
|---|---|---|
| SARS-CoV-2 positivity rate (%) | The SARS-CoV-2 infection was confirmed using the real-time reverse transcriptase polymerase chain reaction of pharyngeal and nasal swab samples, in accordance with the WHO recommendations | 7 years |
| COVID-19 related mortality rate (%) | The COVID-19 related mortality was defined as the termination of isolation due to death. | 7 years |
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Inclusion Criteria:
Exclusion Criteria:
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The Korean nationwide COVID-19 study was a retrospective, nationwide study including all Koreans who tested positive for SARS-CoV-2, aimed at evaluating the characteristics and outcomes of patients with COVID-19. Case patients were defined as individuals over 18 years old with positive results for the SARS-CoV-2 test. For every case patient, we selected up to 20 random controls from the target population who underwent the national health screening.
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| Name | Affiliation | Role |
|---|---|---|
| Dong-Hyuk Cho | Yonsei Wonju Christian Hospital | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31999307 | Result | Phelan AL, Katz R, Gostin LO. The Novel Coronavirus Originating in Wuhan, China: Challenges for Global Health Governance. JAMA. 2020 Feb 25;323(8):709-710. doi: 10.1001/jama.2020.1097. No abstract available. | |
| 32191675 | Result | Cucinotta D, Vanelli M. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020 Mar 19;91(1):157-160. doi: 10.23750/abm.v91i1.9397. |
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The present study are not publicly accessible due to Korean personal information projection act.
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| 32627443 | Result | Kim DW, Byeon KH, Kim J, Cho KD, Lee N. The Correlation of Comorbidities on the Mortality in Patients with COVID-19: an Observational Study Based on the Korean National Health Insurance Big Data. J Korean Med Sci. 2020 Jul 6;35(26):e243. doi: 10.3346/jkms.2020.35.e243. |
| 32454138 | Result | Hamer M, Kivimaki M, Gale CR, Batty GD. Lifestyle risk factors, inflammatory mechanisms, and COVID-19 hospitalization: A community-based cohort study of 387,109 adults in UK. Brain Behav Immun. 2020 Jul;87:184-187. doi: 10.1016/j.bbi.2020.05.059. Epub 2020 May 23. |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D001519 | Behavior |