Neurocognitive Functions of Recovered COVID-19 Patients

An Investigation of Neurocognitive Functions and the Influencing Factors in Recovered Patients With COVID-19

This study is carried on in Wuchang Hospital in Wuhan, China. The investigators plan to recruit 80 patients with COVID-19 and 80 matched healthy control. Using the design of case-control study, the study aims to assess the neurocognitive functions such as executive function and attentional bias in recovered patients with COVID-19 under normal and stress conditions, and to analyze the influencing factors of neurocognitive functions, such as mental health conditions, inflammation indicators and cardiopulmonary function.

Inclusion Criteria:

• Recovered COVID-19 patients or uninfected residents in Wuhan, with an education level above elementary school and are able to complete cognitive tasks;
• Willing to participate in this study and sign informed consent.

Exclusion Criteria:

• Subjects with body temperature> 38°C;
• Subjects who are in menstruation and pregnancy;
• Subjects suffering from cardiopulmonary diseases before the new coronary pneumonia epidemic (such as heart disease, pulmonary hypertension, congestive heart failure, etc.);
• Subjects with severe disturbances in consciousness, cognitive dysfunction, mental disorders, visual and hearing disorders, bone and joint diseases, etc.;
• Subjects with abnormal immune system and severe organ dysfunction (heart, liver, kidney, etc.);
• Subjects who are unwilling to participate in this study and cannot complete all surveys and cognitive function tests.