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| Name | Class |
|---|---|
| Sheba Medical Center | OTHER_GOV |
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the investigators will follow up after patients with neuroendocrine tumors who undergo PRRT treatment and evaluate the response for treatment using PET/CT with different tracers
patients with suspected or biopsy proven NET will undergo imaging using a Combination of 18F- FDG , 18F-DOPA and 68Ga-DOTATATE PET/CT before the stat of PRRT . after two cycles of treatment another two PET/CT are done using 18F- FDG and 18F-DOPA and about 6-8 weeks from last treatment the patient will undergo PET/CT using 18F-DOPA .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PRRT positive | patients who have good response to prrt treatment - the tumor and/or the metastatic disease show no uptake/activity on PET-CT scans | ||
| PRRT negative | no response to PRRT treatment |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with good response to Peptide Receptor Radionuclide Therapy (PRRT) | patients who have clinical and radiological improvement (using RECIST CRITERIA ) | 7 months |
| Number of participants with no response to Peptide Receptor Radionuclide Therapy (PRRT) treatment | patients who have no clinical and radiological improvement or worsening in clinical condition or radiologic findings (RECIST ) | 7 months |
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Inclusion Criteria:
Exclusion Criteria:
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patient with neuroendocrine tumor who were found to be eligible for Peptide Receptor Radionuclide Therapy (PRRT)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| kanana yassin | Contact | 0545680499 | nayruz.knaana@sheba.health.gov.il | |
| domachevsky | Contact | Liran.Domachevsky@sheba.health.gov.il |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sheba Medical Center | Recruiting | Ramat Gan | Israel |
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| ID | Term |
|---|---|
| D018358 | Neuroendocrine Tumors |
| ID | Term |
|---|---|
| D017599 | Neuroectodermal Tumors |
| D009373 | Neoplasms, Germ Cell and Embryonal |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| D009380 | Neoplasms, Nerve Tissue |