Penicillin Allergy Testing in STD Clinics

Validate an Easy to Administer Algorithm to Define Penicillin (PCN-B-lactam) Allergy Status in Sexually Transmitted Disease (STD) Clinic Outpatients

Demonstration project to implement penicillin allergy testing in STD outpatients using a questionnaire and pen allergy testing

all subjects receive risk questionnaire For subjects without high risk responses, randomized to direct oral challenge or PCN skin testing followed by oral challenge

Inclusion Criteria:

• Prior history of PCN allergy

Exclusion Criteria:

• No immunodeficiency or contraindication to skin testing