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This study aims to compare the efficacy of two surgical techniques in treatment of complex anal fistulas. The first technique involves rerouting of the fistula tract with placement of a vessel loop seton around the internal anal sphincter, sparing the external sphincter whereas the second technique entails ligation of inter-sphincteric fistulous tract (LIFT). The main objectives of the study are to assess the success rate, time to healing, change in quality of life, and complications of each procedure including fecal incontinence.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Rerouting seton | Active Comparator | Placement of seton with rerouting of the fistula tract around the internal anal sphincter |
|
| LIFT | Active Comparator | Ligation of the intersphincteric fistula tract |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rerouting seton | Procedure | Excision of superficial fistula tract and placment of seton with rerouting of the fistula tract around the internal anal sphincter |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinical Healing of anal fistula | Clinical healing is assessed by clinical examination during follow-up and is defined as Complete epithelization of the anal wound with no residual fistula tract or external opening or discharge | 12 months after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sameh H Emile, M.D., FACS | Contact | +201006267150 | sameh200@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Sameh H Emile, M.D., FACS | Mansoura University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mansoura university hospital | Recruiting | Al Mansurah | Dakahlia Governorate | 35516 | Egypt |
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| ID | Term |
|---|---|
| D012003 | Rectal Fistula |
| ID | Term |
|---|---|
| D007412 | Intestinal Fistula |
| D016154 | Digestive System Fistula |
| D004066 | Digestive System Diseases |
| D007410 | Intestinal Diseases |
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| LIFT | Procedure | Ligation of the intersphincteric fistula tract |
|
| D005767 | Gastrointestinal Diseases |
| D012002 | Rectal Diseases |
| D005402 | Fistula |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |