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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A00634-35 | Registry Identifier | ID RCB |
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Our goal is to perform a first evaluation of the capabilities of a new generation of non-invasive magnetoencephalography sensors (OPM He4) to record brain magnetic activities. The investigator will record 1) normal subjects stimulated with visual, auditory, somesthesic and motor stimuli and 2) epileptic patient. The investigator will compare the signal to noise ratio of the normal or pathological activities between classical MEG sensors and our OPM He4 prototype.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sensors | Experimental | All subjects will follow the same experimental procedure: a recording using classical MEG followed by a recording in the same condition with the OPM He4 prototype. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MEG recordings | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Signal to Noise Ratio of the recorded brain activities | Volunteers: The signal to noise ratio of normal brain activity following a stimulus will be computed with respect to the pre-stimulus baseline -100ms to -10 ms. Epileptic patient: The signal to noise ratio of abnormal epileptic brain activity will be computed with respect to a 100 ms baseline not containing any abnormal activity. | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Signal to Noise Ratio of pre-frontal auditory activity | evaluate the capacities of MPO to record pre-frontal auditory activities which are not recorded by classical MEG. EEG will be the reference | one month |
| Signal to Noise Ratio of high frequency epileptic activity |
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Inclusion Criteria:
Volunteers:
Patients:
Exclusion Criteria:
Volunteers:
Age < 18 years or > 60
previous neurology or psychiatric pathologies
Child bearing women
Subject having one of the following mettalic parts :
Patients:
Age < 18 years or > 60
previous neurology or psychiatric pathologies except epilepsy
Child bearing women
Subject having one of the following mettalic parts :
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Julien JUNG, MD | Contact | 04.72.35.79.00 | julien.jung@chu-lyon.fr | |
| Denis SCHWARTZ, MD | Contact | 04.72.13.89.61 | denis.schwartz@inserm.fr |
| Name | Affiliation | Role |
|---|---|---|
| Julien JUNG, MD | Hospices Civils de Lyon | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospices Civils de Lyon | Bron | 69500 | France |
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| ID | Term |
|---|---|
| D004827 | Epilepsy |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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|
evaluate the capacities of our MPO to record high frequency epileptic signal which are not recorded by current generation of MPO |
| one month. |
| Comfort of the subject during the MPO He4 recordings for epileptic patient through a short verbal questionary | The evaluation will be done verbally through a short questionary. This questionary evaluates the overall comfort of the MPO system with two questions: 1) An evaluation of the overall comfort thanks to a scale with five steps from very uncomfortable to very comfortable and 2) A comparison with the classical MEG system thanks to a 5 steps scale from much less comfortable than the classical MEG system to much more comfortable. | 5 minutes after the end the recording session |
| Comfort of the subject during the MPO He4 recordings for volunteers through a short verbal questionary | The evaluation will be done verbally through a short questionary. This questionary evaluates the overall comfort of the MPO system with two questions: 1) An evaluation of the overall comfort thanks to a scale with five steps from very uncomfortable to very comfortable and 2) A comparison with the classical MEG system thanks to a 5 steps scale from much less comfortable than the classical MEG system to much more comfortable. | 5 minutes after the end of each recording session |