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| Name | Class |
|---|---|
| Stockholm South General Hospital | OTHER |
A retrospective case-control study. To evaluate if early surgery within 24hours of troch or subtrochanteric hip fractures using intramedullary nailing is safe in patients on warfarin treatment after fast reversal of the warfarin effect
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 99 warfarin patients | warfarin patients were operated within 24 h with a cephalomedullary nail due to a trochanteric or subtrochanteric hip fracture. All patients on warfarin were reversed if necessary to INR≤1.5 before surgery using vitamin K and/or four-factor prothrombin complex concentrate (PCC) | ||
| 99 patients without anticoagulants | As a 1:1 ratio control group matched for age, gender and surgical implant. All patients were operated within 24 h with a cephalomedullary nail due to a trochanteric or subtrochanteric hip fracture. |
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| Measure | Description | Time Frame |
|---|---|---|
| Transfusion rates | Hb value (g/dl) | Pre-surgery |
| Transfusion rates | Transfusion rate (n) | Pre-surgery |
| Transfusion rates | Hb value (g/dl) | During the surgery |
| Transfusion rates | Transfusion rate (n) | During the surgery |
| Transfusion rates | Hb value (g/dl) | 2-4 days after the surgery |
| Transfusion rates | Transfusion rate (n) | 2-4 days after the surgery |
| adverse events | Number of patients with a myocardial infarction, stroke, pulmonary embolism, deep venous thrombosis, sepsis, pneumonia, urinary tract infection, pressure ulcer, or any adverse events. | Immediately after the surgery |
| mortality | The number of deaths | Immediately after the surgery |
| mortality | The number of deaths |
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Exclusion Criteria:
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Patients on warfarin, with low-energi trauma, >60years, mean 86 years Op at Stockholm South General Hospital (södersjukhuset) between (Jan 1,2011 - Dec 31,2014) Follow-up 1 year, all pat op within 24 hours from hospital arrival to the surgery. Operated with Intramedullary nail due to unstable intertrochanteric (OTA/AO 31A2, A3) or Subtrochanteric fracture (OTA/AO 32A,32B,32C).
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| Name | Affiliation | Role |
|---|---|---|
| Leif Mattisson | Stockholm South General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Södersjukhuset | Stockholm | Sjukhusbacken 10 | 11883 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29945596 | Result | Mattisson L, Lapidus LJ, Enocson A. Is fast reversal and early surgery (within 24 h) in patients on warfarin medication with trochanteric hip fractures safe? A case-control study. BMC Musculoskelet Disord. 2018 Jun 26;19(1):203. doi: 10.1186/s12891-018-2126-3. |
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| ID | Term |
|---|---|
| D006620 | Hip Fractures |
| ID | Term |
|---|---|
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D025981 | Hip Injuries |
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| 30-days after the surgery |
| mortality | The number of deaths | 1 year after the surgery |
| D007869 |
| Leg Injuries |