Implications of Different Analgesic Models on Inflammatory Markers After Laparoscopic Cholecystectomy

Implications of Different Analgesic Models on Inflammatory Markers After Laparoscopic Cholecystectomy

Postoperative abdominal and shoulder pain that are experienced in patients undergoing laparoscopic cholecystectomy (LC) is significant. Although it is generally less sever than post open cholecystectomy pain, it still causes an avoidable distress in the first 24 hours postoperatively

The incidence of pain after laparoscopy may be as high as 36 to 63 percent and is attributed to the carbon dioxide gas (CO2) used to induce pneumo-peritoneum1.

The residual part of CO2 remains in the peritoneal cavity for several days after the operation and causes stretching of the phrenic nerve endings, local hypothermia, and diaphragmatic irritation by carbonic acid formation

Inclusion Criteria:

• Patients scheduled for Laparoscopic cholecystectomy.
• Age spectrum of 18 - 55 years
• ASA I, II
• Have no comorbid chronic medical diseases

Exclusion Criteria:

• Patients with co morbid medical diseases
• Age outside the specified range
• Acute inflammation of the gall bladder
• Critically ill patient
• Emergency operations
• Patient refusal