The Effects of Losartan on Social Reward

Losartan Effects on the Social Reward in Humans

The aim of the study is to investigate the effect of losartan (50mg, single dose) on social reward

In a double-blind, between-subject, placebo-controlled design the effects of a single dose of losartan (50mg) on social reward in healthy participants will be examined. 90 minutes after subjects administrate 50mg losartan or placebo, participants will undergo a social incentive delay task. Neural activity will be assessed by the acquisition of functional magnetic resonance imaging (fMRI) data.

Inclusion Criteria:

• Healthy subjects without past or current psychiatric or neurological disorders

Exclusion Criteria:

• history of head injury
• medical or psychiatric illness
• hypertension