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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A02823-36 | Other Identifier | IDRCB |
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There are several clinical presentations of SARS-CoV-2 infection. Among the severe forms, pulmonary involvement with respiratory failure is common. Although severe lung involvement with SARS-CoV-2 meets the Berlin criteria for Acute Respiratory Distress Syndrome (ARDS), it differs from classic ARDS in that compliance (reflecting distensibility of the lung parenchyma) is frequently preserved.
If the interest of Electrical Impedance Tomography has been demonstrated in classical ARDS, this is not the case in ARDS with COVID-19.
However, the use of this technique in this particular patient population would make it possible to distinguish patients with severe hypoxemia linked to derecruitment from those without derecruitment, in whom hypoxemia is more likely to be linked to the loss of hypoxic vasoconstriction.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electrical Impedance tomography | Device | Electrical Impedance tomography recording during 5 minutes every day during 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Coefficient of correlation between the percentage of derecruitment of dependent areas (measured with Electrical Impedance Tomography) and the response to prone position | The percentage of derecruitment of dependent areas will be measured every day with Electrical Impedance Tomography. The response to prone position will be assessed every day. | Up to 7 days |
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Inclusion Criteria:
Exclusion Criteria:
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The study population is composed of patients who have been admitted to the intensive care unit for SARS-CoV-2 ARDS.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital de la Timone | Marseille | 13005 | France | |||
| Hôpital d'Instruction des Armées Sainte-Anne |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35200196 | Derived | Cardinale M, Boussen S, Cungi PJ, Esnault P, Mathais Q, Bordes J, Meaudre E, Goutorbe P. Lung-Dependent Areas Collapse, Monitored by Electrical Impedance Tomography, May Predict the Oxygenation Response to Prone Ventilation in COVID-19 Acute Respiratory Distress Syndrome. Crit Care Med. 2022 Jul 1;50(7):1093-1102. doi: 10.1097/CCM.0000000000005487. Epub 2022 Feb 11. |
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| Toulon |
| 83800 |
| France |
| ID | Term |
|---|---|
| D045169 | Severe Acute Respiratory Syndrome |
| D012128 | Respiratory Distress Syndrome |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012140 | Respiratory Tract Diseases |
| D008171 | Lung Diseases |
| D012120 | Respiration Disorders |
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