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| Name | Class |
|---|---|
| University of Colorado Health | OTHER |
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The NoCo-CoBio Project is a biobanking effort to store and preserve saliva, nasopharyngeal, stool and blood specimens from SARS-CoV-2 PCR (polymerase chain reaction) positive individuals.
The investigators have created a biorepository of stool, saliva, nasopharyngeal swab specimens, peripheral blood mononuclear cells, serum, and plasma from SARS-CoV-2 infected individuals for research purposes. The multifaceted biorepository will be used to establish markers predicting various presentations of COVID-19 (coronavirus disease 2019).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Acute phase of SARS-CoV-2 infection | Participants with an acute SARS-CoV-2 infection. Intervention will not be implemented in this study. | ||
| Convalescent phase of SARS-CoV-2 infection | Participants with a previous diagnosis of SARS-CoV-2 infection, now in the convalescent phase of disease. Intervention will not be implemented in this study. |
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| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of parameters for markers of SARS-CoV-2 infection and predictors for severe disease | Evaluation of parameters for markers of SARS-CoV-2 infection and predictors for severe disease | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of markers and predictors of post acute sequelae of COVID-19 | Evaluation of markers and predictors of post acute sequelae of COVID-19 | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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The investigators aim to enroll individuals who have had a positive SARS-CoV-2 PCR, with a goal of enrolling 100 hospitalized patients with acute SARS-CoV-2 infection, as well as 100 convalescent participants.
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| Name | Affiliation | Role |
|---|---|---|
| Bridget Baxter | Colorado State University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Colorado State University | Fort Collins | Colorado | 80523 | United States | ||
| Poudre Valley Hospital, UCHealth |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41372813 | Derived | Whitcomb LA, Berry K, LaVergne SM, Natter N, Baxter BA, Rao S, Tipton M, Gritsenko MA, Weitz KK, Gerbasi V, Bramer LM, Piehowski PD, Webb TL, Henao-Tamayo M, Chicco AJ, Dunn J, Dutt TS, Ryan EP. Blood pro-thrombotic analytes and platelet activation are associated with post-acute sequelae of COVID-19. BMC Infect Dis. 2025 Dec 10;26(1):61. doi: 10.1186/s12879-025-11824-3. | |
| 36185653 |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D018352 | Coronavirus Infections |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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blood, stool, saliva, nasopharyngeal swab specimens
| Fort Collins |
| Colorado |
| 80523 |
| United States |
| Greeley Hospital, UCHealth | Greeley | Colorado | 80634 | United States |
| Medical Center of the Rockies, UCHealth | Loveland | Colorado | 80538 | United States |
| Derived |
| Stromberg S, Baxter BA, Dooley G, LaVergne SM, Gallichotte E, Dutt T, Tipton M, Berry K, Haberman J, Natter N, Webb TL, McFann K, Henao-Tamayo M, Ebel G, Rao S, Dunn J, Ryan EP. Relationships between plasma fatty acids in adults with mild, moderate, or severe COVID-19 and the development of post-acute sequelae. Front Nutr. 2022 Sep 14;9:960409. doi: 10.3389/fnut.2022.960409. eCollection 2022. |
| 34256735 | Derived | LaVergne SM, Stromberg S, Baxter BA, Webb TL, Dutt TS, Berry K, Tipton M, Haberman J, Massey BR, McFann K, Alnachoukati O, Zier L, Heacock T, Ebel GD, Henao-Tamayo M, Dunn J, Ryan EP. A longitudinal SARS-CoV-2 biorepository for COVID-19 survivors with and without post-acute sequelae. BMC Infect Dis. 2021 Jul 13;21(1):677. doi: 10.1186/s12879-021-06359-2. |
| D014777 |
| Virus Diseases |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |