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The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.
This study was undertaken to investigate the source of these serum tumor markers.
The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.
This study was undertaken to investigate the source of these serum tumor markers.We hypothesis that these tumor markers are released from the lung.
The broncholveolr lvge fluid levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 were measured in the interstitial lung disease patients before lung transplantation. The immunohistochemical test was performed in the specimen lung after lung transplantation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| interstitial lung disease patients | interstitial lung disease patients who need lung transplantation |
| |
| non- interstitial lung disease patients | non- interstitial lung disease patients who need thoracic surgery to remove pneumatocele |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No Intervention | Other | No Intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| serum levels of carcinoembryonic antigen (CEA) | serum levels of carcinoembryonic antigen (CEA) | 6months |
| serum levels of carbohydrate antigen 19-9 (CA19-9) | serum levels of carbohydrate antigen 19-9 (CA19-9) | 6months |
| serum levels of carbohydrate antigen 125(CA125) | serum levels of carbohydrate antigen 125(CA125) | 6months |
| The alveolar lavage fluid levels of carcinoembryonic antigen (CEA) | The alveolar lavage fluid levels of carcinoembryonic antigen (CEA) | 1 week |
| The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9) | The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9) | 1 week |
| The alveolar lavage fluid levels of carbohydrate antigen 125 | The alveolar lavage fluid levels of carbohydrate antigen 125 | 1 week |
| The lung tissue levels of carcinoembryonic antigen (CEA) | The lung tissue levels of carcinoembryonic antigen (CEA) | 1 week |
| The lung tissue levels of carbohydrate antigen 19-9 (CA19-9) |
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Inclusion Criteria
1.Interstitial lung disease patients for lung transplantation
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Exclusion Criteria:
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lung disease patients for lung transplantation
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The First Affiliated Hospital of Guangzhou Medical University | Guangzhou | Guangdong | 520120 | China |
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lung specimen after lung transplantation
The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)
| 1 week |
| The lung tissue levels of carbohydrate antigen 125 | The lung tissue levels of carbohydrate antigen 125 | 1 week |