Efficacy and Safety of Oral Semaglutide Versus Placebo Both in Combination With Metformin and/or Basal Insulin in Children and Adolescents With Type 2 Diabetes
Efficacy and Safety of Oral Semaglutide Versus Placebo Both in Combination With Metformin and/or Basal Insulin in Children and Adolescents With Type 2 Diabetes
This study compares 2 medicines for type 2 diabetes: semaglutide (new medicine) and a dummy medicine (placebo). Semaglutide will be tested to see how well it works compared to the dummy medicine. The study will also test if semaglutide is safe in children and teenagers. Participants will either get semaglutide or the dummy medicine - which one is decided by chance. Participants will take 1 tablet of the study medicine every morning on an empty stomach. They have to wait 30 minutes before they eat, drink or take any other medication by mouth. The study will last for about 1 year and 3 months (66 weeks). Participants will have 12 clinic visits and 8 phone calls with the study doctor. At all 12 clinic visits, participants will have blood samples taken. Participants will also be asked some questions.
Inclusion Criteria:
Exclusion Criteria:
Ostrava-Poruba, 708 00, Czechia
Haidari-Athens, Attica GR-12462, Greece
Penteli, Athens, 15236, Greece
New Dehli, New Delhi 110029, India
Thriruvananthapuram, 695 032, India
Lembah Pantai, Kuala Lumpur 59100, Malaysia
Kiev, 01021, Ukraine
Kyiv, 04114, Ukraine
Vinnytsia, 21010, Ukraine