A Phase III Open-label Extension Study to Evaluate Long-term Safety and Efficacy of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
A Phase III Open-label Extension Study to Evaluate Long-term Safety and Efficacy of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
This study will evaulate the long-term safety, efficacy and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) zinpentraxin alfa, administered by intravenous (IV) infusion to participants with idiopathic pulmonary fibrosis (IPF).
This study is being conducted for the treatment of eligible participants who have taken part in Study PRM-151-202 and received the open-label study drug or completed the Phase III Study WA42293 with PRM-151. Participants who have discontinued treatment from or have completed Study WA42293 and do not want to receive PRM-151 in this study, will be invited to enroll in survival follow-up.
Inclusion Criteria:
Exclusion Criteria:
Celebration, Florida 34747-1818, United States
Iowa City, Iowa 52242, United States
Philadelphia, Pennsylvania 19107, United States
Ciudad Autonoma Buenos Aires, C1284AEB, Argentina
Ciudad Autonoma Buenos Aires, C1426ABP, Argentina
Derqui-Pilar, B1629ODT, Argentina
Florida, Buenos Aires, B1602DQD, Argentina
Mendoza, Mendoza City, M5500CCG, Argentina
Prahan, Victoria 3181, Australia
Beijing, 100050, China
Wuhan, 430030, China
Brest, 29200, France
CHU Hopitaux de Bordeaux, 33000, France
Heraklio, 711 10, Greece
Mezourlo, 41110, Greece
Sotiria Athens, 115 27, Greece
Beersheba, 8410101, Israel
Petach Tiqwa, 4941492, Israel
Bergamo, Abruzzo 24060, Italy
Foggia, Apulia 71122, Italy
Pavia, Lombardy 27100, Italy
Palermo, Sicily 90127, Italy
Siena, Tuscany 53100, Italy
Padova, Veneto 35128, Italy
Treviso, Veneto 31100, Italy
Kawasaki-Shi, Japan
Naka-gun, 319-1113, Japan
Seto-shi, 489-8642, Japan
Tenri-Shi, 632-8552, Japan
Mexico City, Mexico CITY (federal District) 14080, Mexico
Lørenskog, 1478, Norway
Bia?ystok, 15-044, Poland
Lodz, 90-153, Poland
Namdong-gu, 21565, South Korea
Seoul, (0)7345, South Korea
Kaoshiung City, 807, Taiwan
Xitun Dist., 40705, Taiwan
?stanbul, 34093, Turkey (Türkiye)
Istanbul, 34020, Turkey (Türkiye)
Melikgazi/Kayser, 38039, Turkey (Türkiye)
Muratpasa/Antalya, 07059, Turkey (Türkiye)