Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| National Research Foundation of Korea | OTHER |
Not provided
Not provided
Not provided
Not provided
This study aims to establish a prospective cohort of developing pancreas cancer and surveillance MRI protocol. With the focused surveillance protocol, we perform surveillance for pancreas cancer for five years to estimate the risk of pancreas cancer and the clinical feasibility of the surveillance MRI.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Abbreviated PB MRI | Experimental | Short and Focused non-contrast MRI for surveillance |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Abbreviated PB MRI | Diagnostic Test | Annual non-contrast PB MRI. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Detection of pancreas cancer | number of detected pancreas cancer (resectable & BRPC only) in surveillance MRI. | 1 year after the last surveillance MRI. |
| Measure | Description | Time Frame |
|---|---|---|
| Scan time of abbreviated PB MRI for surveillance | table time, in-room time measurement for feasibility | 1 month after the first surveillance MRI. |
| Estimation of pancreas cancer risk | rate of developing pancreas cancer during the study period |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of performance of abbreviated PB MRI | comparison of the rates of pancreas cancer detection between abbreviated MRI and conventional follow-up methods (in available cases) | 1 year after the last surveillance MRI. |
| Identification of super-high risk group of developing pancreas cancer |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jeong Min Lee, MD | Professor | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | 03080 | South Korea |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010190 | Pancreatic Neoplasms |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Gene mutation test |
| Genetic |
K-ras and GNAS mutation test. Being performed once as a baseline test at the enrollment. |
|
| Conventional follow-up | Diagnostic Test | Any of followings: scheduled CECT, MRI, USG, EUS, tumor marker (CA 19-9) during the study period. |
|
| 1 year after the last surveillance MRI. |
| Detection of pancreas cancer | number of detected pancreas cancer of all stages (resectable, BRPC, LAPC, metastatic) in surveillance MRI. | 1 year after the last surveillance MRI. |
Identification of any common radiologic features and gene mutation in participants in whom pancreas cancer develop during the study period. |
| 1 year after the last surveillance MRI. |
| D004066 |
| Digestive System Diseases |
| D010182 | Pancreatic Diseases |
| D004700 | Endocrine System Diseases |