A Study to Evaluate Indocyanine Green Lymphangiography to Improve Lymphadenectomy in Gastric Cancer Patients

Indocyanine Green Lymphangiography as a Tool for Improving Lymphadenectomy in Gastric Cancer

This study will be looking at the safety and added benefit of using the Indocyanine green dye (ICG) during surgery.

Inclusion Criteria:

• Patients ≥ 18 and ≤ 75 years of age.
• Primary gastric adenocarcinoma of any histological subtype confirmed pathologically by endoscopic biopsy.
• Clinical stage tumor T1-4a (cT1-4a), N -/+, M0 at preoperative evaluation according to the American Joint Committee on Cancer (AJCC) Cancer Staging Manual Seventh Edition.
• No distant metastasis, no direct invasion of adjacent organs such as pancreas and spleen in preoperative exams.
• American Society of Anesthesiology score (ASA) class I, II, or III.
• Written informed consent.

Exclusion Criteria:

• Patients ≤ 18 and ≥ 75 years of age.
• History of previous upper abdominal surgery (except laparoscopic cholecystectomy).
• History of previous gastrectomy, endoscopic mucosal resection or endoscopic submucosal dissection.
• History of allergy to iodine agents.
• History of other malignant disease within past five years.
• Emergency surgery due to complication caused by gastric cancer, such as bleeding obstruction or perforation.
• Patients intraoperatively/postoperatively confirmed as T4b.
• Patients intraoperatively confirmed as unable to complete D2 lymph node dissection or R0 dissection.