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The aim of this study is to assess the diagnostic accuracy of CMR feature-tracking (FT) at rest & during stress with low dose dobutamine (LDD) in the evaluation of viability in ischemic cardiomyopathy (ICM) patients and compare it with delayed gadolinium enhancement (DGE).
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI | Diagnostic Test | the patients will underwent dobutamine stress cardiac MRI |
| Measure | Description | Time Frame |
|---|---|---|
| comparison of myocardial strain with late gadolinium enhancement | analysis of the myocardial strain by low dose dobutamine and test if it can assess myocardial viability | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
All patients with a contraindication to MR study:
Patients diagnosed with recent acute coronary syndrome within 4 weeks.
Patients who had contraindications for MRI or contrast agents, and those with poor image quality due to either inadequate breath holding or arrhythmias
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50 patients with chronic LV systolic dysfunction due to coronary artery disease (CAD)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Abdulrahman Hamdan | Contact | 1005363950 | 0020 | abdulrahman.emam@med.au.edu.eg |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31868950 | Background | Bhutani M, Vatsa D, Rahatekar P, Verma D, Nath RK, Pandit N. Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study. Echocardiography. 2020 Jan;37(1):55-61. doi: 10.1111/echo.14567. Epub 2019 Dec 23. | |
| 22130224 | Background |
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| Schuster A, Paul M, Bettencourt N, Morton G, Chiribiri A, Ishida M, Hussain S, Jogiya R, Kutty S, Bigalke B, Perera D, Nagel E. Cardiovascular magnetic resonance myocardial feature tracking for quantitative viability assessment in ischemic cardiomyopathy. Int J Cardiol. 2013 Jun 20;166(2):413-20. doi: 10.1016/j.ijcard.2011.10.137. Epub 2011 Nov 29. |