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Clinical studies found that poor ST-segment resolution (STR) in electrocardiogram (ECG) occurred in major adverse cardiovascular events (MACE), arrhythmia and heart failure was significantly higher . In clinical work, in patients have poor ST-segment decline, the investigators found by CMR-LGE the corresponding myocardium become thinner and other signs of myocardial scar.
The investigators aimed to establish whether poor ST-segment resolution in ECG, as well as CMR-LGE, could detect the presence of myocardial scar in early STEMI patients. In order to provide convenient, cheap and widely used test method for patients who cannot tolerate CMR-LGE.
42 STEMI patients with single-branch coronary artery stenosis or occlusion were enrolled. ST-segment elevations were measured on the baseline and 24 hours after PCI. The study population was divided into two groups by late gadolinium enhanced cardiac magnetic resonance (LGE- CMR), with transmural myocardial scar (>75%) or non-transmural myocardial scar (<75%).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ST-segment resolution <40.15% | ST-segment resolution <40.15% |
| |
| ST-segment resolution >40.15% | ST-segment resolution >40.15% |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ST-segment resolution <40.15% | Diagnostic Test | Forty-two STEMI patients with single-branch coronary artery stenosis or occlusion were enrolled. ST-segment elevations were measured at emergency admission and at 24 h after PCI. Late gadolinium-enhanced cardiac magnetic resonance imaging (CMR-LGE) was performed 7 days after PCI to evaluate myocardial scars. |
| Measure | Description | Time Frame |
|---|---|---|
| ST-segment resolution<40.15% | CMR-LGE was performed to evaluate myocardial scars. | 1) Emergency admission: ST-segment elevations were measured. 2) 24 hours after PCI: ST-segment elevations were measured. 3) 7 days after PCI: CMR-LGE was performed. |
| ST-segment resolution>40.15% | CMR-LGE was performed to evaluate myocardial scars. | 1) Emergency admission: ST-segment elevations were measured. 2) 24 hours after PCI: ST-segment elevations were measured. 3) 7 days after PCI: CMR-LGE was performed. |
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Inclusion Criteria:
Exclusion Criteria:
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42 patients.
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| Name | Affiliation | Role |
|---|---|---|
| Dongying Zhang, phD. | First Affiliated Hospital of Chongqing Medical University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The first affiliated hospital of Chongqing medical university | Chongqing | Chongqing Municipality | 400016 | China |
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| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
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