The Effect of Brain Anatomy on the Efficacy of Brain Stimulation Therapy

The Effect of Brain Anatomy on the Efficacy of Brain Stimulation Therapy

The purpose of this research study is to determine whether brain anatomy impacts the efficacy of transcranial magnetic stimulation (TMS) which is a form of non-invasive brain stimulation. TMS is used to stimulate different areas of the brain and it is well tolerated and generally a safe procedure. It has been studied by researchers for 20 plus years. This brain stimulation device and technique used in this study is an investigational device that has not been approved by the U.S. FDA for treating any muscle or nerve problems. A copy of the device brochure can be found at: https://www.magstim.com/product/rapid-family/

Inclusion Criteria:

• nonimpaired individuals
• free of contraindications for MRI and TMS

Exclusion Criteria:

• musculoskeletal injury of the arm
• neurologic deficit affecting motor or sensory function
• concurrent severe medical illness
• diagnosis of SARS-CoV2, or symptoms consistent with COVID-19, or close contact with someone with SARS-CoV2 in the past 3 weeks