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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A01808-31 | Other Identifier | IDRCB |
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Post-Traumatic Stress Disorder (PTSD) is a public health problem due to both its chronic nature and the low response rate to conventional therapies.
Sleep disorders are the first cause of complaint in patients with PTSD due to night awakenings, difficulty to fall asleep and nightmares.
According to a part of the scientific community, replicative traumatic nightmares represent PTSD's basis mechanism. Traumatic nightmares generate disabling symptoms such as anxiety reactions, while maintaining the symptoms by depriving the individual of good quality sleep. Traumatic nightmares may thus be a sign of PTSD seriousness and chronicity, although their physiological basis remain poorly known.
In the military population, which is highly exposed to psychological traumatism, PTSD prevalence is very high and is associated with severe intensity patterns, a very high frequency of replicative nightmares and a low response to conventional therapies.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PTSD patients | This group is composed of patients suffering from an active PTSD |
| |
| Control group (healthy individuals) | This group is composed of healthy individuals. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sleep recording | Behavioral | Sleep is recorded at home during 7 nights in a row using a connected headband. The participant also has to fill in a sleep agenda every day. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of subjects with a Sleep Efficiency Index (SEI) < 80%. | The sleep efficiency index (SEI) is defined by the ratio TST/TIB with TST being Total Sleep Time and TIB being Time In Bed. TST and TIB will be assessed objectively, at home, using a connected headband (DREEM®, Rythm Paris). A Sleep Efficiency Index (SEI) < 80% is considered to be a poor quality, low-efficiency night. | 1 month after enrollment |
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Inclusion Criteria:
Exclusion Criteria:
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The study population is composed of patients suffering from an active PTSD and healthy individuals.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Emeric SAGUIN, MD | Contact | 143985440 | +33 | emeric.saguin@intradef.gouv.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpoital d'Instruction des Armées Percy | Recruiting | Clamart | 92141 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41689450 | Derived | Feingold D, Quiquempoix M, Remadi M, Sipahimalani G, Lahutte B, Leger D, Gomez-Merino D, Chennaoui M, Saguin E. Physiological markers of Trauma-related nightmares among military personnel suffering from PTSD: A multicenter home-recording study. Psychiatry Clin Neurosci. 2026 May;80(5):398-408. doi: 10.1111/pcn.70038. Epub 2026 Feb 14. | |
| 40370761 |
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| Cognitive tasks | Behavioral | Working memory and inhibition capacity is assessed during computer-based tasks (2-back and Go/No-Go tasks) at enrollment and 1 month after enrollment. |
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| Questionnaires | Other | The participant has to fill in several questionnaires at enrollment and 1 month after enrollment in order to assess:
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| 52e Antenne Médicale | Not yet recruiting | Mailly-le-Camp | 10230 | France |
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| Hôpital d'Instruction des Armées Laveran | Recruiting | Marseille | 13384 | France |
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| 29e Antenne Médicale | Not yet recruiting | Mourmelon-le-Grand | 51400 | France |
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| Hôpital d'Instruction des Armées Bégin | Recruiting | Saint-Mandé | 94160 | France |
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| Hôpital d'Instruction des Armées Sainte-Anne | Not yet recruiting | Toulon | 83000 | France |
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| Saguin E, Feingold D, Sipahimalani G, Quiquempoix M, Roseau JB, Remadi M, Annette S, Guillard M, Van Beers P, Lahutte B, Leger D, Gomez-Merino D, Chennaoui M. PTSD Symptom Severity Associated With Sleep Disturbances in Military Personnel: Evidence From a Prospective Controlled Study With Ecological Recordings. Depress Anxiety. 2025 Apr 25;2025:8011375. doi: 10.1155/da/8011375. eCollection 2025. |
| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D011795 | Surveys and Questionnaires |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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