Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block and erector spinae block and control group. during anaesthesia:total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded.
90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block (SAB) and erector spinae block (ESB) and control group. During anaesthesia: total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded. Other secondary outcomes are: numerical rating scales and postoperative pulmonary functions.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| serratus anterior block | Experimental | serratus anterior block with 20 ml bupivacaine |
|
| erector spinae block | Experimental | erector spinae block with 20 ml bupivacaine |
|
| control group | Sham Comparator | sham block with 20 ml saline |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Serratus anterior block (SAB) | Procedure | Patients will receive a sonar guided serratus anterior plane block with 20 ml of bupivacaine 0.5% |
|
| Measure | Description | Time Frame |
|---|---|---|
| total morphine consumption in first postoperative 24 hours | the amount of morphine required to relieve pain will be recorded | first 24 postoperative hours |
| Measure | Description | Time Frame |
|---|---|---|
| intraoperative fentanyl requirement | the amount of fentanyl required during anaesthesia will be recorded | during anaesthesia |
| numerical rating scale | numerical rating scale (from 0 to 10, where 0 represents no pain and 10 represents the worst imaginable pain) will be recorded in different time intervals during the first 24 hours after surgery |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Mohamed E Hassan, MS | National Cancer Institute - Vairo University - Egypt | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cancer Institute | Cairo | Egypt |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D012965 | Sodium Chloride |
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Erector spinae block | Procedure | Patients will receive a sonar-guided erector spinae plane block with 20 ml of bupivacaine 0.5% |
|
|
| Saline (as a placebo) | Drug | Patients will receive a sham block with 20 ml saline (as a placebo) |
|
| Bupivacaine | Drug | bupivacaine |
|
| the first 24 postoperative hours |
| pulmonary functions | FVC and FEV1 will be recorded at 24 hours after surgery | 24 hours after surgery |
| D017670 |
| Sodium Compounds |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |