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| Name | Class |
|---|---|
| University of Zurich | OTHER |
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The 1-minute sit to stand (1-min STS) test is a standardized test which is used to examine exercise capacity in patients with chronic obstructive pulmonary disease (COPD). The chair seat height used is standardized to 46-48 cm. Using a standard seat height for all patients - irrespective of their body height - may lead to invalid estimates of functional exercise capacity. The objective of this study is to assess whether there is a difference in repetitions during the 1-min STS test if the seat height is adjusted to 90° knee joint angle or the standard height chair of 46 cm is used.
In a single-center, randomized crossover study, the investigators aim to elucidate whether there is a difference in repetitions during the 1-min STS test if the seat height is adjusted to 90° knee joint angle or the standard height chair of 46 cm is used.
Patients with COPD referred for pulmonary rehabilitation will be invited to perform one standardised- (chair seat height 46cm) and one individualized (chair seat height adapted to 90° knee flexion) 1-min STS test on two different days in random order.
The tests will be performed after patients are familiarised with the 1-min STS testing procedure and learning effects can be excluded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1-min STS test: chair seat height adjusted to 90° knee flexion | Experimental | In this experimental condition, the patient performs the 1-minute sit to stand test on an individually adjusted seat height of 90° knee joint flexion. |
|
| 1-min STS test: chair seat height standardized of 46cm | Active Comparator | In this experimental condition, the patient performs the 1-minute sit to stand test on a standard height chair of 46cm. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 1-min STS test: adjusted | Other | Individually adjusted chair seat height of 90° knee joint flexion |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of repetitions in the 1-min STS test | difference in the amount of sit to stand repetitions in the 1-min STS test from a standard chair (46cm) or an individualized seat height chair of 90° knee joint angle | During pulmonary rehabilitation, approximately 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Sit to stand power index | The sit to stand power index is used to calculate the force-generating capacity (in watt) of the knee extensor muscles and is defined as: (leg length (in m) - seat height (in m)) x body mass x acceleration of gravity x sit to stand repetitions / time (sit-stand) (in sec.) | During pulmonary rehabilitation, approximately 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Oxygen saturation | Difference in oxygen saturation profiles between the two experimental conditions | During pulmonary rehabilitation, approximately 14 days |
| Heart rate | Difference in heart rate profiles between the two experimental conditions |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Thomas Riegler, MSc | Berner Reha Zentrum, Heiligenschwendi | Principal Investigator |
| Thomas Radtke, PD, Dr phil | University of Zurich | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Berner Reha Zentrum | Heiligenschwendi | Canton of Bern | 3625 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28254766 | Background | Crook S, Busching G, Schultz K, Lehbert N, Jelusic D, Keusch S, Wittmann M, Schuler M, Radtke T, Frey M, Turk A, Puhan MA, Frei A. A multicentre validation of the 1-min sit-to-stand test in patients with COPD. Eur Respir J. 2017 Mar 2;49(3):1601871. doi: 10.1183/13993003.01871-2016. Print 2017 Mar. | |
| 24620992 | Background |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| 1-min STS test: standardized | Other | Standardized chair seat height of 46 cm |
|
| During pulmonary rehabilitation, approximately 14 days |
| Ratings of perceived exertion | Difference in perceived exertion profiles between the two experimental conditions measured with the category ratio - 10 Borg scale (0-10) | During pulmonary rehabilitation, approximately 14 days |
| Ratings of perceived breathlessness | Difference in perceived breathlessness profiles between the two experimental conditions measured with the category ratio - 10 Borg scale (0-10) | During pulmonary rehabilitation, approximately 14 days |
| Incorrectly performed repetitions during the 1-min STS test | The number of incorrectly performed repetitions during th 1-min STS test | During pulmonary rehabilitation, approximately 14 days |
| Questionnaire about the patient's preferences during the 1-min sit to stand test | Multiple choice questions about patient reported perception concerning sitting position, chair height, perceived difficulties during the 1-min sit to stand test. | During pulmonary rehabilitation, approximately 14 days |
| Yoshioka S, Nagano A, Hay DC, Fukashiro S. Peak hip and knee joint moments during a sit-to-stand movement are invariant to the change of seat height within the range of low to normal seat height. Biomed Eng Online. 2014 Mar 12;13(1):27. doi: 10.1186/1475-925X-13-27. |
| 28621019 | Background | Reychler G, Boucard E, Peran L, Pichon R, Le Ber-Moy C, Ouksel H, Liistro G, Chambellan A, Beaumont M. One minute sit-to-stand test is an alternative to 6MWT to measure functional exercise performance in COPD patients. Clin Respir J. 2018 Mar;12(3):1247-1256. doi: 10.1111/crj.12658. Epub 2017 Jun 15. |
| 22743675 | Background | Quanjer PH, Stanojevic S, Cole TJ, Baur X, Hall GL, Culver BH, Enright PL, Hankinson JL, Ip MS, Zheng J, Stocks J; ERS Global Lung Function Initiative. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J. 2012 Dec;40(6):1324-43. doi: 10.1183/09031936.00080312. Epub 2012 Jun 27. |
| 20522571 | Background | Miller MR, Quanjer PH, Swanney MP, Ruppel G, Enright PL. Interpreting lung function data using 80% predicted and fixed thresholds misclassifies more than 20% of patients. Chest. 2011 Jan;139(1):52-9. doi: 10.1378/chest.10-0189. Epub 2010 Jun 3. |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |