Artificial Sweeteners in Breast Milk

Artificial Sweeteners in Breast Milk: A Clinical Investigation With a Kinetic Perspective

This study will investigate how some artificial sweeteners (AS) cross from blood to breastmilk in breastfeeding women after oral intake. Moreover, it will be investigated whether the kinetics of AS differ based on the women's body composition (BMI) and metabolic status (diabetes). This will be investigated through a clinical trial in which 60 women divided into three groups (normal weight, overweight and diabetic) will drink a beverage containing four AS. over a period of six hours the women will donate blood and breast milk samples in order to investigate the presence of AS.

Inclusion Criteria:

• Above 18 years old
• Able to give consent
• Able to produce enough amounts of breastmilk
• Danish/English speakers
• Pre-pregnancy BMI below 25 (20 subjects)
• Pre-pregnancy BMI above 27 (20 subjects)
• Diabetes type 1 or 2 (20 subjects)

Exclusion Criteria:

• Under the age of 18 years old
• Unable to give consent
• Unable to produce enough amounts of breastmilk
• Non-Danish/English speakers
• If they have consumed artificial sweeteners 24 hours prior to trial