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Patients undergo laryngotracheal anesthesia (LTA) for a variety of in-office laryngology procedures. Prior to resolution of laryngeal sensory anesthesia, oral intake may predispose patients to aspiration. The purpose of this study is to objectively characterize a time period for return of aspiration-free swallow after LTA.
Swallowing is a complex process involving coordination of multiple muscle groups. Sensation in the throat is very important for swallowing safely. Laryngotracheal anesthetic (LTA, or topical application of lidocaine anesthetic to larynx and trachea) is needed for a variety of in-office laryngology procedures, including examination of the air passage, or tracheobronchoscopy. This causes a temporary decrease in sensation that can affect swallow function and result in aspiration (passage of swallowed material into lungs instead of into esophagus and stomach). It is not known how long this effect lasts. It would be helpful to know this for counseling patients on when they can resume swallowing after a procedure. In general, most patients are advised to avoid eating/drinking for 90 minutes after their procedure to allow for sensation to return. To date, there has been no study characterizing the time required for return of aspiration-free swallow after LTA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment Group 1: 90 min waiting period | Participants undergo their planned tracheobronchoscopy + 90 minute waiting period prior to modified functional endoscopic swallowing exam |
| |
| Treatment Group 2: 66 min waiting period | Participants undergo their planned tracheobronchoscopy + 66 minute waiting period prior to modified functional endoscopic swallowing exam |
| |
| Treatment Group 3: 46 min waiting period | Participants undergo their planned tracheobronchoscopy + 46 minute waiting period prior to modified functional endoscopic swallowing exam |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| waiting period | Other | amount of time between clinical procedure and modified functional endoscopic exam of swallowing |
|
| Measure | Description | Time Frame |
|---|---|---|
| Modified functional endoscopic exam of swallowing (FEES) | A modified functional endoscopic exam of swallowing (FEES) is an examination where a small amount of water will be ingested. Each subject will perform about three water swallows. Water will be dyed with green food coloring to facilitate visualization, as is standard with the FEES procedure. If the water passes normally to the esophagus, this will be considered a pass; if the water is aspirated, this will be considered a fail. | Up to 90 minutes |
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Inclusion Criteria:
Exclusion Criteria:
Age less than 18 years
Patients unable or unwilling to provide informed consent
Women who are pregnant
History of abnormal swallowing evaluation, either videofluroscopic study of swallow or functional endoscopic evaluation of swallowing (FEES)
History of medical condition affecting swallowing, such as
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Patients undergoing treatment for airway stenosis who present to the University of Alabama at Birmingham Voice Center.
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| Name | Affiliation | Role |
|---|---|---|
| Blake Simpson, MD | University of Alabama at Birmingham | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | United States |
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| ID | Term |
|---|---|
| D000334 | Aerophagy |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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