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| Name | Class |
|---|---|
| Finnish Pediatric Neurology Association | UNKNOWN |
| Finnish Foundation for Alcohol Studies | OTHER |
| Päijänne Tavastia Central Hospital | OTHER |
| Helsinki University Central Hospital |
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In order to find how many women continue using alcohol during their pregnancies the plan is to anonymously test routine urine samples collected during pregnancies for ethylglucuronide (ETG), a metabolite of ethanol that is detectable in urine up to several days after alcohol consumptions. Altogether 600 samples are taken in the prenatal care units and the prenatal care units dedicated for the alcohol and drug abusing mothers both in the Helsinki and Lahti areas. Test results are used to estimate and compare the prevalence of severe maternal drinking in the different populations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HUCS A | Mothers visiting the prenatal care units within the Helsinki area. | ||
| HUCS HAL | Mothers visiting the prenatal care units dedicated for the alcohol and drug abusing mothers within the Helsinki area. | ||
| PHHYKY A | Mothers visiting the prenatal care units within the Lahti area. | ||
| PHHYKY HALSO | Mothers visiting the prenatal care units dedicated for the alcohol and drug abusing mothers within the Lahti area. |
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| Measure | Description | Time Frame |
|---|---|---|
| EtG | The routine urine samples from the visitors are tested for ethyl glucuronide using dip sticks with 300ng cut off. Positve finds are confirmed in a laboratory. | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Nicotine | The positive EtG urine samples and random negative urine samples from the visitors are tested for nicotine using dip sticks. | Day 1 |
| Cannabis | The positive EtG urine samples and random negative urine samples from the visitors are tested for cannabis using dip sticks. |
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Inclusion Criteria:
Exclusion Criteria:
-
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The study population for the ethylglucuronide (EtG) testing consists of the visitors in the HYKS, PHHYKY and the cities of Helsinki and Lahti prenatal care units, as well as the HYKS and PHHKYKY prenatal care units dedicated for the alcohol and drug abusing mothers (HAL- / HALSO-poliklinikka).
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| Name | Affiliation | Role |
|---|---|---|
| Hanna Kahila, MD | HUCS | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| HALSO-poliklinikka | Lahti | Paijat-Hame Region | 715850 | Finland | ||
| Äitiyspoliklinikka/neuvola |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37349673 | Derived | Jolma M, Koivu-Jolma M, Niemela O, Autti-Ramo I, Kahila H. Rapid urine screening for ethyl glucuronide from pregnant women as a tool for detecting prenatal alcohol exposure. BMC Pregnancy Childbirth. 2023 Jun 22;23(1):464. doi: 10.1186/s12884-023-05789-x. |
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All collected anonymized IPD and the modeling source code will be shared.
6 months after the publication
Scientific study, policy making
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| ID | Term |
|---|---|
| D063647 | Fetal Alcohol Spectrum Disorders |
| ID | Term |
|---|---|
| D005315 | Fetal Diseases |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| OTHER |
| Seinajoki Central Hospital | OTHER |
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urine
| Day 1 |
| Lahti |
| Paijat-Hame Region |
| 715850 |
| Finland |
| HAL-poliklinikka | Helsinki | Uusimaa | 00029 | Finland |
| Äitiyspoliklinikka/neuvola | Helsinki | Uusimaa | 00120 | Finland |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D020751 | Alcohol-Induced Disorders |
| D019973 | Alcohol-Related Disorders |
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |