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| ID | Type | Description | Link |
|---|---|---|---|
| R01EY028755 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Eye Institute (NEI) | NIH |
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The purpose of this study is to see if OCT technology can optimize scleral contact lens fittings. Subjects with keratoconus, post-penetrating keratoplasty (PK), post-LASIK ectasia, post-radial keratotomy (RK), or a variety of anterior surface disorders requiring scleral lens fittings will be considered for enrollment. For each study eye, a clinically-selected scleral lens fit will be compared against an OCT-selected lens fit. The quality of each lens fit will be determined by flourescein exam at the slit lamp. Apical clearance, limbal clearance, conjunctival compression, and lens edge lift will be assessed. A lens that satisfies all four criteria will be considered satisfactory.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Clinically-Selected Scleral Lens | The clinically-selected lens is based on slit lamp assessment. This lens will be compared against an OCT-selected lens. | ||
| OCT-Selected Scleral Lens | The OCT-selected lens is based on OCT measurements. This lens will be compared against a clinically-selected lens. |
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| Measure | Description | Time Frame |
|---|---|---|
| Apical Clearance | Apical clearance of each lens (whether clinically-selected or OCT-selected) will be graded as "acceptable," "too high," or "too low." | 5 years |
| Limbal Clearance | Limbal clearance of each lens (whether clinically-selected or OCT-selected) will be graded as "acceptable," "too much," or "too little." | 5 years |
| Conjunctival Compression | Conjunctival compression of each lens (whether clinically-selected or OCT-selected) will be graded as "acceptable" or "excessive." | 5 years |
| Lens Edge Lift | Lens edge lift for each lens (whether clinically-selected or OCT-selected) will be graded as "acceptable" or "excessive." | 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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Male and female subjects meeting the eye criteria listed above.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Humberto Martinez, COT | Contact | 503-494-7712 | martinhu@ohsu.edu | |
| Denzil Romfh, OD | Contact | 503-494-4351 | romfhd@ohsu.edu |
| Name | Affiliation | Role |
|---|---|---|
| David Huang, MD, PhD | Oregon Health and Science University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oregon Health & Science University, Casey Eye Institute | Recruiting | Portland | Oregon | 97239 | United States |
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| ID | Term |
|---|---|
| D007640 | Keratoconus |
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
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