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The research is aimed at identifying factors of herniation after median laparotomy and developing surgical methods for preventing postoperative ventral hernias and eventrations.
At the first stage, an analysis of the prevalence of postoperative ventral hernias in patients after median laparotomies in urgent surgery will be performed, with the identification of factors contributing to the development of postoperative ventral hernias. At the next stage, the investigators will search for the most reliable methods of suturing the white line of the abdomen, taking into account the risk of hernia formation, with their implementation in patients operated in an emergency through median laparotomic access in comparison with traditionally used methods. In conclusion, an algorithm will be developed for selecting the method of surgical prevention of postoperative ventral hernias, taking into account the risk of their development.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low risk of herniation. | Use of any method of suturing, including modified. |
| |
| The average risk of hernia formation | The application of modified methods of closure of laparotomy wound. |
| |
| high risk of herniation | The use of alloplastic methods of closure of laparotomy wound. |
| |
| The presence of eventrations | The use of alloplastic methods of suturing a laparotomic wound in the absence of suppuration. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Suturing of a laparotomic wound with modified methods | Procedure | Suturing the white line of the abdomen with the help of developed techniques aimed at preventing hernias and eventrations |
| Measure | Description | Time Frame |
|---|---|---|
| Wound complications | Frequency of wound complications in the early postoperative period. | 2 weeks |
| Eventration | Frequency of events in the early postoperative period | 2 weeks |
| Pain syndrome | The severity of pain syndrome in the postoperative scar after midline laparotomy using a verbal scale of pain syndrome | 2 year |
| Postoperative ventral hernia | Frequency of postoperative ventral hernia in the late postoperative period | 2 year |
| Defects in the aponeurosis | Frequency of aponeurosis defects in the late postoperative period | 2 year |
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Inclusion Criteria:
Exclusion Criteria:
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The prospective study included 700 patients, including those operated through a midline laparotomic approach to identify factors of herniation, and those who are planned to have a midline laparotomy in order to choose a rational method of suturing a laparotomic wound, taking into account the risk of incisional hernia formation. Taking into account the degree of risk of postoperative ventral hernia development and the choice of the method of its prevention, the patients were divided into 4 groups.
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| Name | Affiliation | Role |
|---|---|---|
| Alexander Inyutin, PhD MD | RyazSMU | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| RyazSMU | Ryazan | Ryazan Oblast | 390026 | Russia | ||
| RyazSMU |
Undecided Basic demographic data, including sex, age, and ethnicity are to be shared if allowed by the privacy policy.
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 13, 2022 | |
| Reset | Apr 18, 2022 | |
| Release | May 6, 2022 | |
| Reset | Feb 7, 2023 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 13, 2022 | Apr 18, 2022 | |||
| May 6, 2022 |
| ID | Term |
|---|---|
| D004194 | Disease |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Ryazan |
| Russia |
| Feb 7, 2023 |