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This study is a prospective randomized controlled study of different arthroscopic treatments for refractory external humeral epicondylitis combined with platelet rich plasma (PRP) injection. The patients with intractable external humeral epicondylitis were randomly divided into groups before the operation. After the arthroscopic operation was completed, they were divided into a local PRP injection group and a control group (normal saline) to perform additional operations on the damaged tendons, each for up to half a year after the operation. In different time periods, the quantitative and qualitative indicators including pain, functional score, muscle strength, MRI performance, etc. were compared between groups at the same time period to evaluate the difference in the effect of arthroscopic treatment combined with PRP on the treatment of damaged tendons. Determine the effectiveness of PRP. At the same time, in the process of arthroscopic treatment, look for risk factors that affect the curative effect of intractable external humeral epicondylitis, as well as the causes and prevention of common complications.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study group | Experimental | Arthroscopic treatment with PRP injection |
|
| Control group | Placebo Comparator | Arthroscopic treatment with normal saline injection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PRP | Drug | After the arthroscopic operation was completed, a local PRP with 4ml was injected |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Mayo Elbow Performance Score | A score used to evaluated the elbow function, higher scores mean a better outcome. | 3, 6 weeks and 3, 6, 12, 24 months postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Integrity of the tendon in MRI | MRI was performed to identify the status of the tendon | 3, 6, 12, 24 months postoperatively |
| Disability of the Arm, Shoulder, and Hand (DASH) | A score used to evaluated the elbow function, higher scores mean a worse outcome. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yi Lu | Sports Medicine Service, Beijing Jishuitan hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing Jishuitan hospital | Beijing | Beijing Municipality | 100000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40448507 | Derived | Li S, Yang G, Chen R, Li X, Lu Y. Use of Adjunctive Platelet-Rich Plasma for Healing During Arthroscopic Release and Repair for Recalcitrant Lateral Epicondylitis: A Prospective, Double-Blind, Randomized Controlled Trial. Am J Sports Med. 2025 Jul;53(8):1817-1825. doi: 10.1177/03635465251341458. Epub 2025 May 31. |
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| ID | Term |
|---|---|
| D013716 | Tennis Elbow |
| ID | Term |
|---|---|
| D000070639 | Elbow Tendinopathy |
| D052256 | Tendinopathy |
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |
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| normal saline |
| Drug |
After the arthroscopic operation was completed, a local normal saline injection with same ml was performed |
|
| 3, 6 weeks and 3, 6, 12, 24months postoperatively |
| Patient-Rated Tennis Elbow Evaluation (PRTEE) scale | A score used to evaluated the elbow function, higher scores mean a worse outcome | 3, 6 weeks and 3, 6, 12, 24months postoperatively |
| scoring system of Verhaar | A score used to evaluated the elbow function, higher scores mean a better outcome | 3, 6 weeks and 3, 6, 12, 24months postoperatively |
| visual analog scale (VAS) | A score used to evaluated the elbow function, higher scores mean a better | 3, 6 weeks and 3, 6, 12, 24months postoperatively |
| D000092464 |
| Elbow Injuries |
| D001134 | Arm Injuries |
| D014947 | Wounds and Injuries |
| D013708 | Tendon Injuries |