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This study is to investigate whether a candy can increase moisture of the oral cavity and reduce dryness of mouth.
A candy (available on the market from a Swiss manufacturer (Ricola)), free of ingredients that could interfere with the investigation, is tested in five different versions on different days. It is to analyse whether these candies can increase moisture of the oral cavity and reduce dryness of mouth.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| healthy participants starting with candy V01 | Experimental | healthy participants testing a candy in 5 different variations by (unstimulated and stimulated) salivary flow rate (before and after comparison) |
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| healthy participants starting with candy V02 | Experimental |
| |
| healthy participants starting with candy V03 | Experimental |
| |
| healthy participants starting with candy V04 | Experimental |
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| healthy participants starting with candy V05 | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| V01 candy | Other | candy with sweetener (Isomalt) and apple flavour |
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| Measure | Description | Time Frame |
|---|---|---|
| dryness of mouth- sensation | dryness of mouth- sensation by Visual analogue scale (VAS); 0 = does not apply; 10 = is absolutely true. | one point assessment following consumption of candy (approx 5 minutes) |
| Change in salivary flow rate (ml/min) | Change in salivary flow rate (ml/min) before and after stimulation (mechanical and gustatory) by consumption of candy | before and after consumption of candy (approx 5 minutes for each salivary flow measurement) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andreas Filippi, Prof. Dr. med. dent. | Universitäres Zentrum für Zahnmedizin Basel | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universitäres Zentrum für Zahnmedizin Basel | Basel | 4058 | Switzerland |
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| ID | Term |
|---|---|
| D014987 | Xerostomia |
| ID | Term |
|---|---|
| D012466 | Salivary Gland Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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doppel- blind testing of 5 different variations of a candy in each participant by (unstimulated and stimulated) salivary flow rate; each participant is testing each variation of candy once in a randomized order at 5 consecutive days
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| V02 candy | Other | candy with with sweetener (Isomalt) and apple flavour and acidifying agent (apple acid + citric acid) |
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| V03 candy | Other | candy with with sweetener (Isomalt) and apple flavour and acidifying agent (apple acid + citric acid) and Vitamin C |
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| V04 candy | Other | candy with sweetener (Isomalt) (control group 1) |
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| V05 candy | Other | candy with with sweetener (Isomalt) and acidifying agent (apple acid + citric acid) (control group 2) |
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