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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
| Sioux Falls VA Health Care System | FED |
| Bay Pines VA Healthcare System | FED |
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The present study seeks to increase understanding of Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD) among veterans, an important public health concern. We will study the effects of regulatory deficits and sleep disturbance on the dynamic course of PTSD and AUD. The study will investigate whether a short, computerized training in the laboratory will alter maladaptive response biases and reduce associations between sleep disturbance, affect and behavioral dysregulation, AUD symptoms, and PTSD symptoms in the real world.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Alcohol Cognitive Bias Modification (CBM) + PTSD CBM | Experimental |
| |
| Alcohol CBM + PTSD Sham | Experimental |
| |
| Alcohol Sham + PTSD CBM | Experimental |
| |
| Alcohol Sham + PTSD Sham | Sham Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alcohol CBM | Behavioral | Trains approach or avoidance responses to alcohol cues. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Rate of Alcohol Use Disorder Symptoms | These are experience sampling items derived from Diagnostic and Statistical Manual of Mental Disorders (DSM-5). | 2 years |
| Rate of PTSD Symptoms | These are experience sampling items derived from the PTSD Checklist from DSM-5 (PCL-5). | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jeffrey S Simons, PhD | Contact | 605-658-3710 | jeffrey.simons@usd.edu | |
| Raluca M Simons, PhD | Contact | 605-658-3710 | raluca.simons@usd.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bay Pines VA Health Care System | Not yet recruiting | Bay Pines | Florida | 33744 | United States |
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| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| D000437 | Alcoholism |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
| D019973 | Alcohol-Related Disorders |
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| ID | Term |
|---|---|
| D000431 | Ethanol |
| ID | Term |
|---|---|
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
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| PTSD CBM | Behavioral | Trains approach or avoidance responses to trauma cues. |
|
| Alcohol Sham | Behavioral | Will not train approach or avoidance responses. |
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| PTSD Sham | Behavioral | Will not train approach or avoidance responses. |
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| Sioux Falls VA Health Care System | Recruiting | Sioux Falls | South Dakota | 57105 | United States |
|
| The University of South Dakota | Recruiting | Vermillion | South Dakota | 57069 | United States |
|
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |