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| Name | Class |
|---|---|
| National Nanotechnology Center (NANOTEC), The National Science and Technology Development Agency (NSTDA) | UNKNOWN |
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This study will evaluate new technique, microneedle, to detect latent tuberculosis (TB) in healthy volunteers
The cross-sectional study to investigate the effect of microneedle formulations and lengths of Tuberculin PPD microneedles on the delayed-type hypersensitivity response in healthy volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| volunteers | Other | two different types of diagnostic tools (TST vs microneedle) will be used to screen for latent TB infection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TST vs PPD microneedle test | Diagnostic Test | TST vs First patch: 800 um in length, PPD1 formulation; Second patch: 1,500 um in length, PPD1 formulation; Third patch: 800 um in length, PPD2 formulation; and Fourth patch: 1,500 um in length, PPD2 formulation |
| Measure | Description | Time Frame |
|---|---|---|
| size of induration at 48 hours post-PPD injection | Monitoring the response of delayed-type hypersensitivity on the skin by comparing TST to microneedle tests | 48 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sivaporn Gatechompol, MD | The HIV Netherlands Australia Thailand Research Collaboration | Principal Investigator |
| Jeerapond Leelawattanachai, PhD | King Chulalongkorn Memorial Hospital | Principal Investigator |
| Saradee Warit, PhD | King Chulalongkorn Memorial Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine, Chulalongkorn University | Bangkok | 10330 | Thailand |
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| ID | Term |
|---|---|
| D055985 | Latent Tuberculosis |
| ID | Term |
|---|---|
| D014376 | Tuberculosis |
| D009164 | Mycobacterium Infections |
| D000193 | Actinomycetales Infections |
| D016908 | Gram-Positive Bacterial Infections |
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| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
| D000085343 | Latent Infection |