Counting and classification of blood cells in a bone marrow smear and peripheral blood smear are essential to clinical hematology. To this date, this procedure has been carried out in a manual manner in the great majority of clinical settings. There is often inconsistency in the counting result between different operators largely due to its manual nature. There has not been an effective and standard method for blood smear preparation and automatic counting and classification. The recent advent of deep neural network for medical image processing introduced new opportunities for an effective solution of this long-standing problem. Numerous results have been published on the effectiveness of convolutional neural network in clinical image recognition task.

Inclusion Criteria:

• Patients who have suspected or confirmed hematological diseases and receive bone
• marrow or peripheral blood cell morphological examination in National Taiwan University Cancer Center
• Patients who are aged more than 20 y/o

Exclusion Criteria:

•Patients who are not willing to sign informed consents

Patients who have suspected or confirmed hematological diseases and receive bone marrow or peripheral blood cell morphological examination in National Taiwan University Cancer Center