Prevention Interventions for Opioid Misuse

Optimized Interventions to Prevent Opioid Use Disorder Among Adolescents and Young Adults in the Emergency Department

The purpose of the study is to develop and test innovative interventions to prevent the development of opioid misuse and opioid use disorders among older adolescents and young adults (AYA; ages 16-30) who use opioids, which will be initiated from a health care visit in the emergency department and extended post discharge via a telehealth approach. This study will have significant impact by identifying optimal, cost-effective opioid prevention strategies to sustain outcomes among AYAs.

Inclusion Criteria:

• Aged 16-30 years
• Seeking care in Michigan Medicine emergency department (ED)
• Ability to read/comprehend and communicate in English
• Medically & cognitively able to provide consent or assent
• Prescription opioid use plus >=1 other risk factor (misuse positive for marijuana, other illicit drugs, other prescription drug misuse; binge drinking; depression or suicidality) or opioid misuse [prescription opioid misuse or illicit opioid use (e.g., heroin, fentanyl)]

Exclusion Criteria:

• Presenting with acute sexual assault, acute suicidality or a current cancer diagnosis/are currently receiving cancer treatment
• Current pregnancy at baseline
• History of injection drug use within last 12 months
• High risk for opioid use disorder
• Enrolled in Aim 1