End-Tidal Carbon Dioxide Monitoring Device for Sedation During Endoscopic Ultrasonography

The Effect of A Novel End-Tidal Carbon Dioxide Monitoring Device for Sedation During Endoscopic Ultrasonography-Guided Fine Needle Aspiration

To meet the needs of both operators and patients, moderate and deep sedation has been widely used in digestive endoscopy, which is invasive and painful. With its pleasant effects, sedation has complications nevertheless. And respiratory depression is the most common one, which makes respiratory monitoring significant. SpO2 and respiratory motion are regularly monitored without satisfying timeliness or sensitivity. Capnography with current device is only able to detect either oral or nasal breathing. The present study was designed to test the effect of the investigator's modified End-Tidal Carbon Dioxide (ETCO2) monitoring device for sedation during endoscopic ultrasonography-guided fine needle aspiration.

Inclusion Criteria:

• Scheduled for ultrasonography-guided fine needle aspiration
• Adult patients aged 18 to 65 years
• American Society of Anesthesiologists (ASA) Physical Status Classification I-III
• Subjects provide informed consent

Exclusion Criteria:

• Full stomach or upper gastrointestinal tract obstruction
• Baseline pulse oximetric saturation (SpO2) <95% while breathing room air
• Obesity （BMI≥28kg/m2）or anticipated difficult airway
• Cardiovascular or cerebrovascular events within 3 months
• Pregnancy
• Chronic opioid user
• Allergic to anesthetics