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This study is to analyse the demographics and microbiological factors concerning patients undergoing cardio surgical intervention using CPB complicated with bloodstream infection (BSI) postoperatively.
Infectious complications after cardiovascular surgery, especially in operations that use cardiopulmonary bypass (CPB), is associated with significant morbidity and increase in peri-operative mortality. Prolonged CPB usage could be predictive for early bloodstream infection following cardia surgery. This study is to analyse the demographics and microbiological factors concerning patients undergoing cardio surgical intervention using CPB complicated with bloodstream infection (BSI) postoperatively.
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of bloodstream infection (BSI) in postoperative period (clinical evidence of sepsis with laboratory-confirmed bacteraemia from blood sample) | Incidence of bloodstream infection (BSI) in postoperative period (clinical evidence of sepsis with laboratory-confirmed bacteraemia from blood sample) | within 7 days after a cardiovascular surgery |
| Extracorporeal circulation time during surgery (minutes) | Extracorporeal circulation time during surgery (minutes) | one time assessment at baseline |
| In-hospital mortality (number) for patients with BSI vs those without BSI after a cardiovascular surgery | In-hospital mortality is defined as death before discharge | during hospital stay (usually up to 4 weeks) |
| Surgical intervention rate (Incidence of cardiovascular re-operation) during the initial hospital stay (number) | Surgical intervention rate (Incidence of cardiovascular re-operation) during the initial hospital stay | during hospital stay (usually up to 4 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of cardiovascular events (stroke, myocardial infarction) during hospitalization | Incidence of cardiovascular events during hospitalization | during hospital stay (usually up to 4 weeks) |
| Incidence of cardiovascular events (stroke, myocardial infarction) during follow-up |
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Inclusion Criteria:
Exclusion Criteria:
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Patients having suffered from sepsis after cardiac surgery in a period between 2009 and 2019 will be evaluated.
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| Name | Affiliation | Role |
|---|---|---|
| Denis Berdajs, Prof. Dr. med. | Klinik für Herzchirurgie, University Hospital Basel | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinik für Herzchirurgie, University Hospital Basel | Basel | 4031 | Switzerland |
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| ID | Term |
|---|---|
| D018805 | Sepsis |
| D003428 | Cross Infection |
| ID | Term |
|---|---|
| D007239 | Infections |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
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Incidence of cardiovascular events (stroke, myocardial infarction) during follow-up |
| after hospital discharge until follow- up assessment (up to 10 years) |
| Incidence of cardiovascular re-operation during the follow up | Incidence of cardiovascular re-operation during the follow up | after hospital discharge until follow- up assessment (up to 10 years) |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D007049 | Iatrogenic Disease |
| D020969 | Disease Attributes |