This study investigates the retinal vascular features, using optical coherence tomography angiography, in patients during one year's follow up after the endoscopic endonasal surgery to remove an intra-suprasellar pituitary adenoma compressing the optic nerve.

The role of the optical coherence tomography angiography to detect the changes in retinal vascular networks in patients after 48 hours and 1 year from the endoscopic endonasal surgery to remove an intra-suprasellar pituitary adenoma compressing the optic nerve.

The optical coherence tomography angiography allows a detailed and quantitative analysis of the retinal vascular networks and to follow their changes over time.

Inclusion Criteria:

• age older than 45 years
• diagnosis of pituitary adenoma
• treatment-naive with endoscopic endonasal pituitary surgery
• absence of other neurological disease
• absence of vitreoretinal and vascular retinal diseases

Exclusion Criteria:

• age younger than 45 years
• No diagnosis of pituitary adenoma
• previous treatment with endoscopic endonasal pituitary surgery
• presence of neurological disease
• presence of vitreretinal and vascular retinal diseases

The partecipants were older than 45 years and they underwent long term follow up after endoscopic endonasal pituitary surgery to remove pituitary adenoma.

They did not present other neurological and ophthalmological diseases