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Lack of ability to communicate with the study population
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The purpose of this study is to see if Exparel, used intraoperatively by injecting at the surgical site, followed by a Supraclavicular nerve block with bupivacaine in the recovery room, will provide better pain scores for patients at 24 and 48 hours post operatively than, 1)Bupivacaine Hydrochloride (HCL) injection at the surgical site, with a supraclavicular block in Post-anesthesia care unit(PACU), or 2)a supraclavicular block in PACU without any kind of injection at the surgical site.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exparel plus supraclavicular block | Experimental |
| |
| Bupivacaine HCL plus supraclavicular block | Active Comparator |
| |
| supraclavicular block only | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Group A (Exparel plus supraclavicular block) | Drug | Patients will receive 20 cc (266 mg) of Exparel injected in the distal radius area and a supraclavicular block in the recovery room.The supraclavicular blocks will be ultrasound guided and consist of 20 cc of Bupivacaine HCl 0.25% .Anesthesiologist performing the block will be instructed to surround the brachial plexus with the local anesthetic, taking special care to inject in the "corner pocket". |
| Measure | Description | Time Frame |
|---|---|---|
| Pain as measured by the Revised American Pain Society Patient Outcome Questionnaire (APS-POQ-R) | The questionnaire consists of 13 questions.The first 11 is scored form 0-10(a higher number indicating a worse outcome). | 24 hours post treatment |
| Pain as measured by the Revised American Pain Society Patient Outcome Questionnaire (APS-POQ-R) | The questionnaire consists of 13 questions.The first 11 is scored form 0-10(a higher number indicating a worse outcome). | 48 hours post treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Number of patients who presented to Emergency room following surgery for pain control | 24 hours post surgery | |
| Number of patients who presented to Emergency room following surgery for pain control | 48 hours post surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Erikka L Washington, MD | The University of Texas Health Science Center, Houston | Principal Investigator |
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| Group B (Bupivacaine HCL plus supraclavicular block) | Drug | Patients will receive 20 cc of Bupivacaine 0.25% (50mg) in the distal radius area.In the recovery room the patient will be given the supraclavicular block which will be ultrasound guided and consisting of 20 cc of Bupivacaine HCl 0.25% .Anesthesiologist performing the block will be instructed to surround the brachial plexus with the local anesthetic, taking special care to inject in the "corner pocket". |
|
| Group C(supraclavicular block only) | Drug | In the recovery room the patient will be given the supraclavicular block which will be ultrasound guided and consisting of 20 cc of Bupivacaine HCl 0.25% .Anesthesiologist performing the block will be instructed to surround the brachial plexus with the local anesthetic, taking special care to inject in the "corner pocket". |
|
| Number of over the counter(OTC) pain medications consumed by the patient | 24 hours post surgery |
| Number of OTC pain medications consumed by the patient | 48 hours post surgery |
| Number of prescription opioid medications consumed by the patient | 24 hours post surgery |
| Number of prescription opioid medications consumed by the patient | 48 hours post surgery |
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
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