Dopamine Versus Norepinephrine Under General Anesthesia

Hemodynamic Effects of Dopamine Versus Norepinephrine Under General Anesthesia in Infant With Congenital Heart Disease

Participants under general anesthesia will be randomly treated with an adjusted dose dopamine or norepinephrine to elevate 10% of mean arterial pressure. Systemic hemodynamic data is recorded by PRAM and the change of cardiac index is compared between groups.

After intubation under general anesthesia, radial arterial is cannulated and pressure transducer is connected to MostCare(core technique PRAM). CI, SVRI, SVI, SVV, dp/dt and HR are recorded before and after a infusion of dopamine or norepinephrine to elevate 10% of mean arterial pressure. Changes of these hemodynamic data are compared.

Inclusion Criteria:

• undertake cardiac surgery for congenital heart disease

Exclusion Criteria:

• Aortic valve or aortic disease
• severe arrhythmia
• use of cardiovascular active drugs before anesthesia
• need to use a combination of different cardiovascular support drugs after anesthesia