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| Name | Class |
|---|---|
| University Heart Center Freiburg - Bad Krozingen | OTHER |
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The EPIC registry is an observational multicentre registry evaluating the technical feasibility of retrograde CTO-PCI using epicardial collateral connections. It will evaluate the frequency, effectiveness, safety and outcomes of patients who underwent CTO-PCI using this approach. The EPIC registry retrieves data from CTO centres across Germany.
The EPIC registry is the first German-wide observational multicentre registry evaluating the technical feasibility, clinical success and safety of retrograde CTO-PCI using epicardial collateral connections. The EPIC registry retrieves data from CTO centres across Germany. All patients will be followed-up to 30 days after inclusion.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Retrograde Percutaneous Coronary Intervention of Chronic Total Occlusion | Procedure | Retrograde CTO-PCI using epicardial collateral connections |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of technically successful retrograde CTO-PCI using epicaridal collaterals | defined as the rate of successful CTO-PCI with reestablished antegrade coronary flow (thrombolysis in myocardial infarction (TIMI) flow III) with less than residual stenosis of 50%. | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of clinically successful retrograde CTO-PCI using epicaridal collaterals | Clinical success is defined as the rate of successful CTO-PCI by technical success without MACCE and without major periprocedural complications, including pericardial tamponade and contrast induced dialysis. | 30 days |
| Rate of failed retrograde CTO-PCI using epicaridal collaterals |
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Inclusion Criteria:
Exclusion Criteria:
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EPIC will observationally evaluate all patients undergoing retrograde CTO-PCI using epicardial collateral connections during daily clinical practice from German CTO centres.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Michael Behnes, Prof. Dr. | Contact | +49 621 383 6239 | michael.behnes@umm.de | |
| Kambis Mashayekhi, Dr. | Contact | +49 7633 402 2100 | Kambis.Mashayekhi@universitaets-herzzentrum.de |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Medical Centre Mannheim | Recruiting | Mannheim | Baden-Wurttemberg | 76149 | Germany |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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is defined as the rate of CTO-PCI without technical success defined as residual stenosis >50% (by visual estimation) and TIMI flow grade <3 after CTO-PCI. |
| 30 days |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |