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| Name | Class |
|---|---|
| Software AG Stiftung | UNKNOWN |
| Universität Freiburg | UNKNOWN |
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The present study is a sub-study of the ENTAiER study. The ENTAiER study is a multicenter, randomized, controlled study to evaluate the efficacy and safety of eurythmy therapy and Tai Chi in comparison to standard care in chronically ill older patients with an increased risk of falling.
In addition to the main questions of the ENTAiER study, three additional questions are being investigated at the Hospital Essen-Steele: Proteome and telomere analyses as well as qualitative parameters are recorded and examined. The aim is to compare the changes in proteomes, telomeres and qualitative factors under eurythmy therapy, Tai Chi and standard care in chronically ill older patients with an increased risk of falling.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Eurythmy therapy exercises | Experimental | As part of the ENTAiER trial: In group sessions á 5 patients with a qualified therapist: In the first 3 months twice a week, in the second 3 months once a week. Recommendation to practice at home on at least 3 days per week (optimal, practice daily). They are supported by an eurythmy manual and an exercise video. This supplements the regular care. |
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| Tai Chi exercises | Experimental | As part of the ENTAiER trial:In group sessions of 5 patients each with a qualified teacher: In the first 3 months twice a week, in the second 3 months once a week. Recommendation to practice at home on at least 3 days per week (optimal, practice daily). They are supported by a Tai Chi Manual and an exercise video. This complements the regular care |
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| Standard Care Only | Active Comparator | As part of the ENTAiER trial:Brochure with detailed description of various evidence-based measures for fall prevention, prepared for the specific age group (https://www.trittsicher.org/files/trittsicher\_bzga\_sturzpraevention\_2015-11-23.pdf) - Recommendation to visit the family doctor and discuss fall prophylaxis with her |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Eurythmy Therapy | Other | A mindfulness-oriented movement therapy |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in proteomic analysis from baseline to after intervention | A maximum of 500 µL plasma is used for the proteomic studies. The proteins are digested tryptically, a concentration determination is performed by amino acid analysis and the peptide samples are then measured by different mass spectrometric methods (data dependent (DDA) and independent detection (DIA), proteome-wide prediction of peptide tandem mass spectra by deep learning (Prosit), etc.). The results obtained are then verified by Western blot, ELISA and/or a targeted mass spectrometric method (parallel reaction monitoring) | Before intervention (week 0) and after intervention (6 months) |
| Change in telomer analysis from baseline to after intervention | The telomere length is determined from blood samples using quantitative real-time PCR (TaqMan) from genomic DNA. | Before intervention (week 0) and after intervention (6 months) |
| Qualitative parameter | By means of semi-structured interviews of maximum 60 minutes per participant, the effects of the intervention are to be recorded qualitatively. | After intervention (6 months) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kliniken Essen-Mitte | Essen | 45276 | Germany |
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| Label | URL |
|---|---|
| Main study | View source |
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| ID | Term |
|---|---|
| D002908 | Chronic Disease |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D026302 | Tai Ji |
| D059039 | Standard of Care |
| ID | Term |
|---|---|
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026241 | Exercise Movement Techniques |
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| Tai Chi |
| Other |
A martial art developed in China, which in recent times is often regarded as a system of movement theory or gymnastics |
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| Standard Care | Other | Treatment process that a clinician should follow for a certain type of patient |
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| D026741 |
| Physical Therapy Modalities |
| D019984 | Quality Indicators, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
| D017530 | Health Care Quality, Access, and Evaluation |