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The purpose of this study is to demonstrate that allowing infants that require high flow nasal cannula (HFNC)/Continuous positive airway pressure (CPAP) to orally feed if demonstrating oral cues will achieve full oral feeds faster.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oral Feed Intervention Group | Experimental |
| |
| Usual care | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oral Feed | Dietary Supplement | Infant will be seen by occupational therapist (OT) twice a week and assessed for oral cues. If infant shows oral cues then the occupational therapist will proceed with feeding strategies. Oral feeding strategies include pacifier dips, open nipple trials with syringe controlled bolus size (1-4mls) and po trials up to 10mls. |
| Measure | Description | Time Frame |
|---|---|---|
| Post menstrual Age (PMA) once full oral feeds are achieved as documented by not requiring gavage tube feeds for at least 24 hours | Measured in the electronic medical record | 2 months after enrollment |
| Measure | Description | Time Frame |
|---|---|---|
| PMA at hospital discharge | up to 6 months after admission | |
| PMA at completion of first oral feed | 1 month after enrollment. | |
| length of hospitalization |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ashley N Morin, MD | Contact | (713) 500-5800 | Ashley.N.Morin@uth.tmc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Ashley N Morin, MD | The University of Texas Health Science Center, Houston | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Texas Health Science Center at Houston | Recruiting | Houston | Texas | 77030 | United States |
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| ID | Term |
|---|---|
| D047928 | Premature Birth |
| ID | Term |
|---|---|
| D007752 | Obstetric Labor, Premature |
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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|
| Usual care | Dietary Supplement | Infants will not start oral feeds until on HFNC 2 Litres or less. Oral feeds will be started on the discretion of the physician. |
|
| up to 6 months after admission |
| number of gastrostomy tube | up to 6 months after admission |
| oxygen at discharge | up to 6 months after admission |
| safety outcomes during the feed as measured by the number of desaturations | 2 months after enrollment |
| safety outcomes during the feed as measured by the number of apnea episodes | 2 months after enrollment |
| safety outcomes during the feed as measured by the number of bradycardia episodes | 2 months after enrollment |
| safety outcomes as measured by the increase in fraction of inspired oxygen (FiO2) during and after feed | 2 months after enrollment |
| safety outcomes as measured by the increase in flow after feed | 2 months after enrollment |
| safety outcomes as measured by the number of choking episodes | 2 months after enrollment |
| safety outcomes as measured by the number of episodes of aspiration pneumonia | 2 months after enrollment |
| D000091642 | Urogenital Diseases |