Interest in Clonidine in Association With Levobupivacaine Performing a Pudendal Block in Proctological Surgery.

Interest in Clonidine in Association With Levobupivacaine Performing a Pudendal Block in Proctological Surgery: Pilot Study, Prospective

Proctological surgery represents a short duration surgery performed in ambulatory, which causes significant post-operative pain.

Post-operative pain resulting from proctological surgery is greater than 5 on the Visual Analog Scale (VAS) within the first 24 hours and it revives during the first defecation.

The ideal pain management procedures are based on the multimodal analgesia model, based in turn on the combination of products and / or techniques to improve the quality of analgesia, reduce the side effects linked to the use of opioids, reduce responses to surgical stress, reduce postoperative recovery and allow rapid rehabilitation of the patient.

The aim of our study is to investigate whether clonidine combined with levobupivacaine in the pudendal block reduce the total consumption of opioids in proctological surgery.

Inclusion Criteria:

• Age ≥ 18 years
• Signature of informed consent

Exclusion Criteria:

• Refusal to participate ;
• Allergy to either local anaesthetics or clonidine;
• Local infectious pathologies (e.g. acute ano-perineal suppuration)
• Pregnancy
• Breastfeeding
• Severe bradyarrhythmia due to sinus node disease or second and third degree atrioventricular block
• Severe depressive condition
• Severe coronary artery disease
• Raynaud's disease
• Heart failure
• Obliterating thromboangiitis
• Epilepsy
• Spinal anesthesia