Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Acute compartment syndrome (ACS) is defined as a clinical entity originated from trauma or other conditions, and remains challenging to diagnose and treat effectively. Threre is the controversy in diagnosing, treating ACS. It was found that there was no criterion about the ACS, and result unnecessary osteotomy. The presence of clinical assessment (5P) always means the necrosis of muscles and was the most serious or irreversible stage of ACS. Besides pressure methods, the threshold of pressure identifying ACS was also controversial.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| fractures with blister appeared | tibial plateau fractures with blister observed |
| |
| fractures without blister appeared | tibial plateau fractures without blister observed |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fasciotomy | Procedure | if it was suspected with ACS, the fasciotomy was conducted. but if the blister observed, it means decreased conmpartment sydrome. therefore, the blister observed can avoid unnecessary fasciotomy to patients suspected with ACS |
| Measure | Description | Time Frame |
|---|---|---|
| injury mechanism | The relative data was collected about injury mechanism such as high falling accident, traffic accident, fall from standing height,Crushing | up to 1 weeks |
| the time when the blister appeared | The relative data was collected about the time when the blister appeared after injury | up to 4 weeks |
| time to reconstructive surgery | The relative data was collected about time to reconstructive surgery | time to when the surgery was conducted after 2 weeks |
| union time | The relative data was collected about union time | through study completion, an average of 1 year |
| No non-anatomic gap or step (larger than 5 mm) | The relative data was collected about complications | through study completion, an average of 1 year |
| secondary loss of reduction | The relative data was collected about complications | through study completion, an average of 1 year |
| Deep venous thrombosis | The relative data was collected about complications | through study completion, an average of 1 year |
| superficial wound problems |
| Measure | Description | Time Frame |
|---|---|---|
| CK levels | CK levels | through hospitalization completion, an average of 1 month |
| chloride levels | chloride levels | through hospitalization completion, an average of 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| LKS score | Lysholm knee score | through study completion, an average of 1 year |
| VAS scores | visual analogue scale | through study completion, an average of 1 year |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
The severe tibial plateau (â…¤and â…¥ according to Schatzker's classification) in our hospital who will be treated with open internal fixation in our hospital
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guo Jialiang, Doctor | Contact | 18203222090 | drjlguo86@gmail.com | |
| Ma Lijie, Doctor | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Hou Zhiyong, Doctor | Hebei Medical University Third Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| the Third Hospital of Hebei Medical University | Recruiting | Shijiazhuang | Hebei | 050000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31277147 | Background | Guo J, Yin Y, Jin L, Zhang R, Hou Z, Zhang Y. Acute compartment syndrome: Cause, diagnosis, and new viewpoint. Medicine (Baltimore). 2019 Jul;98(27):e16260. doi: 10.1097/MD.0000000000016260. | |
| 36715712 | Derived | Wang T, Yang S, Guo J, Long Y, Hou Z. Predictors of muscle necrosis in patients with acute compartment syndrome. Int Orthop. 2023 Apr;47(4):905-913. doi: 10.1007/s00264-023-05699-9. Epub 2023 Jan 30. |
Not provided
Not provided
acute compartment syndrome
2 years after the experiment was conducted
all authors focusing on ACS research
Not provided
Not provided
| ID | Term |
|---|---|
| D000092463 | Tibial Plateau Fractures |
| ID | Term |
|---|---|
| D000092443 | Knee Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D013978 | Tibial Fractures |
Not provided
Not provided
| ID | Term |
|---|---|
| D000071938 | Fasciotomy |
| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
Not provided
Not provided
Not provided
Not provided
Not provided
The relative data was collected about complications |
| through study completion, an average of 1 year |
| blister skin immunochemistry and immunofluorescence analysis | CK1, 5, 10, claudin 1, 2 and occludin as determined by immunochemistry analysis, and skin barrier proteins; claudin 1, 2 and occludin was determined by immunofluorescence analysis and qPCR. | through study completion, an average of 1 year |
| UREA levels | UREA levels | through hospitalization completion, an average of 1 month |
| D007718 |
| Knee Injuries |
| D007869 | Leg Injuries |