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To date, no published systematic review and meta-analysis has compared AHI-CPAPflow and AHI-PSGgold. Therefore, the primary objective of this study is to compare published data for AHI-PSGgold and AHI-CPAPflow in patients treated by CPAP.
The secondary objectives are to evaluate, in a manner similar to the primary objective, data for apnoea indices (AI), hypopnoea indices (HI), respiratory disturbance indices (RDI) and respiratory effort related arousals (RERAs) and to perform subgroup analyses focusing on the inclusion/exclusion of central apnoea patients, BMI levels, CPAP device brands, pressure titration modes, use of a predetermined and fixed pressure level or not, and the impact of a 4%-PSG desaturation criteria versus 3%-PSG on index accuracy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The study population | All (full scientific) study designs and publication types written in English and reporting Bland-Altman test results (or other tests suggesting the presence of the required data) between simultaneous, paired, polysomnography (PSG)-derived AND Continuous Positive Airway Pressure (CPAP)-derived data describing sleep disordered breathing. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Continuous Positive Airway Pressure | Device | Continuous Positive Airway Pressure device deployed for at least one night synchronously with polysomnography. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The mean difference between AHI-CPAPflow and AHI-PSGgold | AHI-CPAPflow = Apnoea-Hypopnoea-Indices Determined Via Continuous Positive Airway Pressure AHI-PSGgold = Apnoea-Hypopnoea-Indices Determined by Polysomnography | Day 0 |
| The standard deviation for the mean difference between AHI-CPAPflow and AHI-PSGgold | Day 0 |
| Measure | Description | Time Frame |
|---|---|---|
| The mean difference between AI-CPAPflow and AI-PSGgold | AI-CPAPflow = Apnoea--Indices Determined Via Continuous Positive Airway Pressure AI-PSGgold = Apnoea--Indices Determined by Polysomnography | Day 0 |
| The standard deviation for the mean difference between AI-CPAPflow and AI-PSGgold |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients treated with a CPAP-device and synchronous polysomnography.
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| Name | Affiliation | Role |
|---|---|---|
| Dany Jaffuel, MD,PhD | University Hospitals of Montpellier | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospitals of Montpellier | Montpellier | 34925 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33972338 | Background | Bertelli F, Suehs CM, Mallet JP, Rotty MC, Pepin JL, Gagnadoux F, Matzner-Lober E, Bourdin A, Molinari N, Jaffuel D. Apnoea-hypopnoea indices determined via continuous positive airway pressure (AHI-CPAPflow) versus those determined by polysomnography (AHI-PSGgold): a protocol for a systematic review and meta-analysis. BMJ Open. 2021 May 10;11(5):e044499. doi: 10.1136/bmjopen-2020-044499. |
| Label | URL |
|---|---|
| Meta IAHflow on the Open Science Framework. | View source |
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| ID | Term |
|---|---|
| D012891 | Sleep Apnea Syndromes |
| ID | Term |
|---|---|
| D001049 | Apnea |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D020919 | Sleep Disorders, Intrinsic |
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| ID | Term |
|---|---|
| D045422 | Continuous Positive Airway Pressure |
| D017286 | Polysomnography |
| ID | Term |
|---|---|
| D011175 | Positive-Pressure Respiration |
| D012121 | Respiration, Artificial |
| D058109 | Airway Management |
| D013812 | Therapeutics |
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| Polysomnography | Device | Polysomnography deployed for at least one night synchronously with Continuous Positive Airway Pressure. |
|
| Day 0 |
| The mean difference between HI-CPAPflow and HI-PSGgold | HI-CPAPflow = Hypopnoea--Indices Determined Via Continuous Positive Airway Pressure HI-PSGgold = Hypopnoea--Indices Determined by Polysomnography | Day 0 |
| The standard deviation for the mean difference between HI-CPAPflow and HI-PSGgold | Day 0 |
| The mean difference between RDI-CPAPflow and RDI-PSGgold | RDI-CPAPflow = Respiratory Disturbance Indices Determined Via Continuous Positive Airway Pressure RDI-PSGgold = Respiratory Disturbance Indices Determined by Polysomnography | Day 0 |
| The standard deviation for the mean difference between RDI-CPAPflow and RDI-PSGgold | Day 0 |
| The mean difference between RERA-CPAPflow and RERA-PSGgold | RERA-CPAPflow = Respiratory Effort Related Arousals Determined Via Continuous Positive Airway Pressure RERA-PSGgold = Respiratory Effort Related Arousals Determined by Polysomnography | Day 0 |
| The standard deviation for the mean difference between RERA-CPAPflow and RERA-PSGgold | Day 0 |
| D020920 |
| Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
| D012138 |
| Respiratory Therapy |
| D008991 | Monitoring, Physiologic |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |