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Endovascular thrombectomy is the standard of care for acute ischaemic stroke due to large-vessel occlusion. Current guidelines for periprocedural anaesthesiological care give gross recommendations on management of stroke patients during recanalization, but lack detailed information.
To determine how anaesthesiologists support endovascular thrombectomy with regard to anaesthetic technique, choice of substances, haemodynamic management, and ventilation. With a multivariate analysis, the investigators will look for the factors of anesthetic management that are independently correlated with a good or bad outcome.
see brief summary
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Endovascular thrombectomy | there is only one group of the subjects that had stroke and went under thrombectomy procedure and to see how anaesthesiologists support endovascular thrombectomy with regard to anaesthetic technique,choice of substances, haemodynamic management, and ventilation. |
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| Measure | Description | Time Frame |
|---|---|---|
| Neurological outcome 90 days after the stroke | Neurological outcome is measured using the modified Rankin Scale [0-6], with higher values indicating worse outcome. As a Primary Outcome Measure, the scale will be dichotomized into good (modified Rankin Scale ≤ 2) versus poor (modified Rankin Scale > 2) outcome. | 90 days |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Mortality rate 90 days after the stroke. Mortality rate is the percentage of patients that have died within 90 days following their stroke. | 90 days |
| Grade of recanalization | Recanalization is classified according to the modified Thrombolysis in Cerebral Infarction classification (mTICI) [0 - 3], with higher values indicating better reperfusion. |
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Inclusion Criteria:
Exclusion Criteria:
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The target population consists of patients undergoing emergency endovascular thrombectomy for treatment of AIS-LVO. The planned minimum sample size is 5,000 patients.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Andreas Ranft, Dr. | Contact | 004989 4140 9632 | andreas.ranft@tum.de |
| Name | Affiliation | Role |
|---|---|---|
| Andreas Ranft, Dr. | Senior Physician-München, Germany | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| TU München | Recruiting | München | Germany |
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| ID | Term |
|---|---|
| D002545 | Brain Ischemia |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| sixty minutes |
| Duration | Duration [minutes] from patient's arrival in angiography suite to arterial puncture for endovascular thrombectomy. Duration [minutes] from patient's arrival in angiography suite to arterial puncture for endovascular thrombectomy. Duration [minutes] from arterial puncture to end of endovascular thrombectomy. | 30 Minutes |
| Proportion of patients breathing spontaneously | Proportion of patients breathing spontaneously after thrombectomy [Time Frame: On transfer from angiography suite after thrombectomy, which typically takes 1 hour]. This is defined as percentage of patients that breathe spontaneously without laryngeal mask, laryngeal tube, or endotracheal tube after thrombectomy. | sixty minutes |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |