Evaluation of Brain Activity Changes After a Behavior Change Weight Loss Intervention

Evaluation of Brain Activity Changes After a Behavior Change Weight Loss Intervention

The aim of this study is to compare brain changes in individuals with overweight or obesity enrolled in either the Noom Healthy Weight program or a matched control. The study objectives (primary and secondary) are to measure brain change reported as ERP and EEG data over a 16-week timeframe. Additionally, we will explore changes in the default mode network (resting-state asymmetry in EEG measurements), changes in executive functioning, quality of life, mood, and salivary markers as they relate to EEG data.

Inclusion criteria:

• Each subject must be able to understand and provide informed consent
• Between the ages 18-60 years
• Self-report of good health
• Overweight or obesity (BMI ≥ 25)
• Able to meet our criteria of adherence to the program
• Able to attend in-person visit in Long Island, NY

Exclusion criteria:

• Inability or unwillingness to give written informed consent or comply with the study
• Visual impairment that cannot be corrected with glasses or contact lenses
• Any indication of drug, alcohol or medicine abuse.
• Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data
• Presence of a brain injury, psychiatric disorders, seizure disorders, and other neurological conditions
• Reported eating disorder
• Currently pregnant or 6 months postpartum
• Planning to become pregnant within the next 5 months