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The aim of this pilot was to study how body water behaves between the different internal water pools of the human body, what the role and influence of the interstitium is and what the effect is of body position on the distribution and allocation of BW between different body parts (trunk, legs, arms). To study this, 2 techniques that have not been used before in urological research were tested on their usefulness:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bio Impedance assesement (BIA) | Diagnostic Test | BIA every 5 minutes od the test protocol. Patients stood up for 5 minutes, laid down for 70 minutes, followed by 5 minutes in a seated position and ending with 30 minutes standing. BIA was done every 5 minutes. | ||
| Blood and salava sample | Diagnostic Test | Blood Samples were done at the initation of the protocol, and every 10 minutes after ingestion of the deutarated water | ||
| Ingestion of deuterated water | Dietary Supplement | 15 minutes after the intiation of the test protocol, participants drink an amount of deuterated water corresponding with 0.25% of their TBW calculated using the Watson Formula | ||
| Urine sample | Diagnostic Test | A urine sample is taken at the initiation and after termination of the protocol. |
| Measure | Description | Time Frame |
|---|---|---|
| Observing the absorption time, and the lay over time from deuterated water from the gast of deuterated water in the blood | Aim of this overview is to assess how fast the deuterium oxide ingested in the human gastro-intestinal tractus, the colon and the blood pool. We want to know if this is 5min or even more 30 min and when the maximal dose of deuterium in the blood is reached. | 3 hours |
| Observing impedance changes linked with position switch | Decrease of impedance by 1 amplitude by changing positions grom standing to lying. | 5 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Urology, Ghent University | Ghent | 9000 | Belgium |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |